Protein Alignment cad and nkx2.3

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_571498.1
• Gene: nkx2.3 / 30698
• ZFINID: ZDB-GENE-990415-178
• Length: 321
• Species: Danio rerio
• Alignment Length: 326
• Identity: 81/326 - (24%)
• Similarity: 125/326 - (38%)
• Gaps: 73/326 - (22%)

  Fly   178 LPSP----PITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNN-------NNNNSPSTHN 231
            ||||    |.:|  .:|......|......|..:||........:...       ...:||...:
Zfish     3 LPSPVTSTPFSV--KDILKLEQQTRQLQSLHPASHHAQLHPELQDRFQAPSSCFLGGGDSPGFSD 65

  Fly   232 NNN-----NNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLED-------------- 277
            |..     |:.|:.::...|...||.|      .:||....|......|||
Zfish    66 NEEKMSFLNSLSMQDSLVESSLSPPMF------VHPALGHVDTKLEDELEDHETKSCGAILRTPE 124

  Fly   278 -----LSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKI 337
                 .|| .:.:.:.||:.|.||:::..|..|||:.:...||::...:..||.||.|:..||||
Zfish   125 CEAEVHSD-TERAQRQRTRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASTLKLTSTQVKI 188

  Fly   338 WFQNRRAKERKQNKKGS----------DPNVMGVGVQHAD------YSQLLDAKAKLEPGLHL-- 384
            ||||||.|.::|.:..:          .|..:.|.|...|      .||..:....:.||.:.
Zfish   189 WFQNRRYKCKRQRQDKTLEMAGHHHPPPPRRVAVPVLVRDGKPCLTGSQSYNTTYAVNPGPYTYN 253

  Fly   385 ---SHSLAHSMNPMAAMNIPAMRLHPHLAAHSHSLAAVAAHSHQL----QQQHSAQMSAAAAVGT 442
               |::.|...||.:. ..|::   |.|.|::.:.|.::...:.|    |.|.|.....:|..||
Zfish   254 GYSSYNNAAYTNPYSC-TYPSL---PPLPANTSTNALMSMSLNNLGTYSQPQTSQGTPVSACQGT 314

  Fly   443 L 443
            |
Zfish   315 L 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	25/54 (46%)
nkx2.3	NP_571498.1	Homeodomain	143..199	CDD:459649	25/55 (45%)