Protein Alignment cad and dlx2b

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_571372.1
• Gene: dlx2b / 30557
• ZFINID: ZDB-GENE-980526-18
• Length: 276
• Species: Danio rerio
• Alignment Length: 309
• Identity: 74/309 - (23%)
• Similarity: 119/309 - (38%)
• Gaps: 81/309 - (26%)

  Fly   170 HQQHIAEGLPSPPITVSGSEISSPGAPTS--------ASSPHHHLA----HHLSAVANNNNNNNN 222
            |..||.....|   ||..|: .||..|.|        :||...|.|    ..|::.:.:.....|
Zfish    13 HTNHITSSSFS---TVHKSQ-DSPTLPVSTVTDSSFFSSSQTGHCAGTAYAQLASYSYHPGTVGN 73

  Fly   223 NNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGK 287
            .:.||..::....::..:.....:.|.|.          |.:|:.: .|.|.:..:      :||
Zfish    74 VHYSPKAYDLGYASSYGAYGTYGASSSPT----------PTEPEKE-ESEPEVRMV------NGK 121

  Fly   288 TRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKK 352
            .:...|.|.:|:.||...|::.:..::|:.:..::|||.:|.|::.||||||||||:|.:|..|.
Zfish   122 PKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKLWKN 186

  Fly   353 GSDPNVMGVGVQHADYSQLLDAKAKLEPGLHLSHSLAHSMNPMAAMNIPAMRLH----------- 406
            |..|                 |..::..|    .|.:.|..|.|..:.|.....
Zfish   187 GEIP-----------------ADQQVASG----DSPSSSPPPQAGWDFPPNPTQNDGDTVSEQPT 230

  Fly   407 --PHLAAHS-------HSLAAVAAH---SHQLQQQHSAQMSAAAAVGTL 443
              |:..|.|       :|......|   |..:|..||:.||    .||:
Zfish   231 GPPNTTAPSFLTNYSWYSSTNAVTHLQPSTLIQPHHSSAMS----TGTI 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	23/54 (43%)
dlx2b	NP_571372.1	DLL_N	29..102	CDD:463567	13/73 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	97..123		8/42 (19%)
		Homeodomain	126..182	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	191..238		8/50 (16%)