DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cad and noto

DIOPT Version :9

Sequence 1:	NP_001260641.1	Gene:	cad / 35341	FlyBaseID:	FBgn0000251	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_571130.1	Gene:	noto / 30260	ZFINID:	ZDB-GENE-990415-75	Length:	241	Species:	Danio rerio

Alignment Length:	258	Identity:	58/258 - (22%)
Similarity:	90/258 - (34%)	Gaps:	72/258 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 SAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPST 229
            ||.|.||.:                      .||:|.|....:..:.|:.       ...:....
Zfish    14 SARPLHQDY----------------------ATSSSKPSTGKSFTIDALL-------ARPDQAEM 49

  Fly   230 HNNNNNNNSVSNNNRTSP-------SKPPYFDWMK-----KPAYPAQPQPDLSSSPNLEDLSDLL 282
            ....|...|::|....|.       |:.|:|.:.:     :..||....|..:............
Zfish    50 RERTNAYRSITNQTPVSSSALPLIYSQMPHFAYSQSIMQTQTGYPVFCYPPYNFQTTCRGAVYAQ 114

  Fly   283 DA--------------SGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSER 333
            ||              |||::   :.|..:|:.|...||||:...:|:....:..||..|.|:|.
Zfish   115 DAVLAKAAVHSHYKHKSGKSK---RMRTSFTNDQLSRLEKEFARQQYMVGSERFLLASALQLTEA 176

  Fly   334 QVKIWFQNRRAKERKQN---------KKG-----SDPNVMGVGVQHADYSQLLDAKAKLEPGL 382
            |||:||||||.|.|||:         |.|     ..|...|...:..|:::..|....::..|
Zfish   177 QVKVWFQNRRIKWRKQSLEQQQAKLAKLGLTVPPKSPGSQGREDEERDFTEESDVDIDIDDSL 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeobox	295..347	CDD:278475	23/51 (45%)
noto	NP_571130.1	COG5576	79..>193	CDD:227863	34/116 (29%)
noto	NP_571130.1	Homeobox	138..190	CDD:278475	23/51 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900