Protein Alignment cad and Hoxd4

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001099355.1
• Gene: Hoxd4 / 288153
• RGDID: 1309690
• Length: 251
• Species: Rattus norvegicus
• Alignment Length: 301
• Identity: 91/301 - (30%)
• Similarity: 119/301 - (39%)
• Gaps: 92/301 - (30%)

  Fly   124 GSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPP--NHQQHIAEGLPSPPITVS 186
            ||.:.|.....|.| ......|....||||       .|||||.|  .|.|.     ||.|
  Rat    38 GSGAQGSDFQPPGL-YPRPDFGEQPFGGGG-------PGPGSALPARGHGQE-----PSGP---- 85

  Fly   187 GSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPP 251
            ||..|:||.|..|..|                       :|..       .:.:.:..|.|.:||
  Rat    86 GSHYSAPGEPCPAPPP-----------------------APLP-------GARACSQPTGPKQPP 120

  Fly   252 YFDWMKKPA--YPAQPQPDLSS-SPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTS 313
            ....:|:||  ||...:..::| :||.        ..|:.:   :.|..||..|.||||||:..:
  Rat   121 PGTALKQPAVVYPWMKKVHVNSVNPNY--------TGGEPK---RSRTAYTRQQVLELEKEFHFN 174

  Fly   314 RYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKAKL 378
            ||:|.||:.|:|.||.|||||:||||||||.|.:|.:|.   ||..|
  Rat   175 RYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKL---PNTKG------------------ 218

  Fly   379 EPGLHLSHSLAHSMNPMAAMNIPAMRLHPHLAAHSHSLAAV 419
                 .|.|.:.|.:..||   |:..|.|....|...|..:
  Rat   219 -----RSSSSSSSCSSSAA---PSQHLQPMAKDHHTDLTTL 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	33/54 (61%)
Hoxd4	NP_001099355.1	Homeodomain	153..209	CDD:459649	33/58 (57%)