Protein Alignment cad and NKX2-8

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_055175.2
• Gene: NKX2-8 / 26257
• HGNCID: 16364
• Length: 239
• Species: Homo sapiens
• Alignment Length: 148
• Identity: 43/148 - (29%)
• Similarity: 66/148 - (44%)
• Gaps: 27/148 - (18%)

  Fly   246 SPSKPPYFDWM--KKPAYPAQPQ-------PDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDF 301
            :|...|...|:  ::..||:..:       ||.|..|:....|...||    ..:.|.||:::..
Human    34 APQPDPCAAWLDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDA----EKRKKRRVLFSKA 94

  Fly   302 QRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGS--DPNVMGVGVQ 364
            |.||||:.:...||::...:.:||..|.|:..||||||||.|.|.::....|:  .|::......
Human    95 QTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAEL 159

  Fly   365 HADYSQLLDAKAKLEPGL 382
            ||            .|||
Human   160 HA------------APGL 165

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	24/54 (44%)
NKX2-8	NP_055175.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..87		12/56 (21%)
		Homeodomain	85..141	CDD:459649	24/55 (44%)