Protein Alignment cad and Gbx1

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_056554.1
• Gene: Gbx1 / 231044
• MGIID: 95667
• Length: 418
• Species: Mus musculus
• Alignment Length: 444
• Identity: 96/444 - (21%)
• Similarity: 144/444 - (32%)
• Gaps: 170/444 - (38%)

  Fly    99 PTSAHQLMQQHHHHHAHA----SSSSASSGSSSS------GGAPGAPQLNETNSSIGVGGAGGGG 153
            |..|....::|....|.:    |:..|..|..|:      |||||           |.||:.||.
Mouse    27 PHCAEPAPRRHLGPRARSEPCVSARGARRGPGSAMQRAAGGGAPG-----------GSGGSSGGP 80

  Fly   154 GVGGATDGGPGSAPPNHQQHIAEGLPS----------------------PPITV----------- 185
            |...:.|...|..||.....:..|.|.                      ||:..
Mouse    81 GAAFSIDSLIGPPPPRSGHLLYTGYPMFMPYRPLVLPQALAPAPLPAGLPPLAPLASFAGRLSNT 145

  Fly   186 ----SGSEISSPGA-----PTSASSPH-HHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSV- 239
                .|..:.|..|     |:.|..|. ::....|:|.|  .:..:.:|..|:....:...::.
Mouse   146 FCAGLGQAVPSMVALTTALPSFAEPPDAYYGPPELAAAA--ASTASRSNPEPAARRTDGALDAEE 208

  Fly   240 -----SNNNRTSPSKPPYFDWMKKPAYPAQ----------------------------------- 264
                 .......|..||:|. ...|:.||:
Mouse   209 LLPAREKVTEPPPPPPPHFS-ETFPSLPAEGKVYSSDEEKLEPPAGDPAGSEQEEEGSGGDSEDS 272

  Fly   265 --------------PQPDLSSSP--NLED----LSDLLDASGKTRTKDKYRVVYTDFQRLELEKE 309
                          |:|.|..||  ..|:    .:.:....||:|.:   |..:|..|.||||||
Mouse   273 FLDSSAGGPGALLGPKPKLKGSPGTGAEEGTPVATGVTTPGGKSRRR---RTAFTSEQLLELEKE 334

  Fly   310 YCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDA 374
            :...:|:::..:|::|..|.|||.|||||||||||| .|:.|.|:..:..|..|:
Mouse   335 FHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAK-WKRIKAGNVSSRSGEPVR---------- 388

  Fly   375 KAKLEPGLHLSHSLAHSMNPMAAMNIPAMRLHPHLAAHSHSLAAVAAHSHQLQQ 428
                              ||...:.||         .|.:..|..:.| .|::|
Mouse   389 ------------------NPKIVVPIP---------VHVNRFAVRSQH-QQMEQ 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	28/54 (52%)
Gbx1	NP_056554.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..90		20/73 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..320		16/109 (15%)
		Homeodomain	317..373	CDD:459649	29/59 (49%)