DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cad and alr-1

DIOPT Version :9

Sequence 1:	NP_001260641.1	Gene:	cad / 35341	FlyBaseID:	FBgn0000251	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_509860.1	Gene:	alr-1 / 181302	WormBaseID:	WBGene00044330	Length:	362	Species:	Caenorhabditis elegans

Alignment Length:	223	Identity:	57/223 - (25%)
Similarity:	94/223 - (42%)	Gaps:	54/223 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 AHHLSAVANNNN--NNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDL 269
            |..::|:.||.:  ..::...:|:..|.....:.:.|....|||                   |.
Worm    60 AFSIAALTNNQHELKEDDGKKTPTGDNILEAASVLDNRENGSPS-------------------DG 105

  Fly   270 SSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQ 334
            ::||         |.:|| |.:.:||..::.||..||||.:..:.|..:..:.|||..:.|:|.:
Worm   106 TNSP---------DDNGK-RKQRRYRTTFSAFQLDELEKVFARTHYPDVFTREELATRVQLTEAR 160

  Fly   335 VKIWFQNRRAKERKQ----------------NKKGSDPNVMGVGVQHADYSQLLDAKAK--LEPG 381
            |::||||||||.|||                |..|.:|..|.:. |.|.::.:....|.  |...
Worm   161 VQVWFQNRRAKYRKQERSSTHHPYQAPMSIPNSNGDNPYQMMLS-QEAIFAAINQQAAAHLLNEQ 224

  Fly   382 LHLSHSLAHSMNPMAAMNIPAMRLHPHL 409
            :.::.|...|.:|    ::|.....|.|
Worm   225 VRIATSDRRSQSP----SVPVTTSSPIL 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeobox	295..347	CDD:278475	22/51 (43%)
alr-1	NP_509860.1	Homeobox	121..174	CDD:365835	22/52 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910