DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cad and vab-15

DIOPT Version :9

Sequence 1:	NP_001260641.1	Gene:	cad / 35341	FlyBaseID:	FBgn0000251	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_509648.1	Gene:	vab-15 / 181197	WormBaseID:	WBGene00006881	Length:	225	Species:	Caenorhabditis elegans

Alignment Length:	249	Identity:	48/249 - (19%)
Similarity:	85/249 - (34%)	Gaps:	115/249 - (46%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 QQHIAEGLPSP-PITVS---------------GSE-----------------ISSPGAPTSASSP 202
            :|...|.||.| |||..               |::                 :||..:|.|.:|.
Worm    24 KQKCREDLPKPTPITPKTPMLIPGLHPMTPYFGAQLDPVMIYFAQTGNRLPIVSSDSSPESCASS 88

  Fly   203 HHHLAHHLSAVANNNNNNNNNNNSP----------STHNNNNNNNSVSNNNRTSPSKPPYFDWMK 257
            ...:.|.|..:::...::..::::.          ..|.||                       :
Worm    89 PLSMQHSLQWLSSQREDSPTSDDAKIQIGLSKCMLRKHKNN-----------------------R 130

  Fly   258 KPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKS 322
            ||..|...|                                   |.:.||:::.:.:|::|..::
Worm   131 KPRTPFSTQ-----------------------------------QLISLERKFQSKQYLSIAERA 160

  Fly   323 ELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKA 376
            |.:.:|.|:|.||||||||||||.::              :|.|:..::..|:|
Worm   161 EFSASLQLTETQVKIWFQNRRAKSKR--------------LQEAEVEKVKFAQA 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeobox	295..347	CDD:278475	21/51 (41%)
vab-15	NP_509648.1	Homeobox	132..185	CDD:278475	24/87 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810