Protein Alignment cad and Msx3

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_034966.1
• Gene: Msx3 / 17703
• MGIID: 106587
• Length: 204
• Species: Mus musculus
• Alignment Length: 260
• Identity: 64/260 - (24%)
• Similarity: 94/260 - (36%)
• Gaps: 87/260 - (33%)

  Fly   142 SSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHI-AEGLPSPPITVSGSEISSPGA--PTSASSPH 203
            ::..:..||.....||.|:.||  .|.:.:..: ||.:|       |||....|.  |..||.|
Mouse     4 ATFDMNAAGLEARGGGHTEHGP--LPFSVESLLEAERVP-------GSESGELGVERPLGASKP- 58

  Fly   204 HHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPD 268
                                                       .:.||.......|..|:.|...
Mouse    59 -------------------------------------------GAWPPPVAHSCPPRAPSPPPCT 80

  Fly   269 LSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSER 333
            |.                |.:|..|.|..:|..|.|.||:::...:|::|..::|.:.:|||:|.
Mouse    81 LR----------------KHKTNRKPRTPFTTAQLLALERKFHQKQYLSIAERAEFSSSLSLTET 129

  Fly   334 QVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQL-LDAKAKLEPGLHLSHSLAHSMNPMAA 397
            ||||||||||||.::              :|.|:..:| |.||..|.....|...|...::..||
Mouse   130 QVKIWFQNRRAKAKR--------------LQEAELEKLKLAAKPLLPAAFALPFPLGTQLHSSAA 180

  Fly   398  397
            Mouse   181  180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	26/54 (48%)
Msx3	NP_034966.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..89		17/116 (15%)
		Homeodomain	88..144	CDD:459649	26/55 (47%)