Protein Alignment cad and egl-5

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001021166.1
• Gene: egl-5 / 176093
• WormBaseID: WBGene00001174
• Length: 223
• Species: Caenorhabditis elegans
• Alignment Length: 222
• Identity: 62/222 - (27%)
• Similarity: 99/222 - (44%)
• Gaps: 30/222 - (13%)

  Fly   188 SEISSPGAPTSASSP--HHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTS-PSK 249
            |..||....|::|.|  :.||:...:........:...:::|||..:.....|.:...... |..
 Worm    13 STASSAATSTTSSQPDANDHLSRLAAMTQGVGKEDPETSSTPSTEASLYPGISAAYMQSYGWPQN 77

  Fly   250 PPYFDWMKKPA-YPAQPQ--PDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYC 311
            ..||.....|| :|..||  |: ::.||..:|.    ||.|     |.|..|..:|...||.::.
 Worm    78 YNYFGQPLGPATFPGWPQCYPN-TAWPNYGELF----ASSK-----KGRQTYQRYQTSVLEAKFQ 132

  Fly   312 TSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKA 376
            .|.|::.:::.||.....|::||:||||||||.|.:|:.::..|         |.:::.||.|..
 Worm   133 QSSYVSKKQREELRLQTQLTDRQIKIWFQNRRMKAKKEKQRVDD---------HTEHTPLLPANP 188

  Fly   377 KLEPGLHLSH----SLAHSMNPMAAMN 399
            ....|:.:..    .:|| ..|.||.|
 Worm   189 PKGMGMDMDDEKKWQMAH-WPPAAAHN 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	22/54 (41%)
egl-5	NP_001021166.1	Homeodomain	113..169	CDD:459649	23/60 (38%)