Protein Alignment cad and DLX3

DIOPT Version :9

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_005211.1
• Gene: DLX3 / 1747
• HGNCID: 2916
• Length: 287
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 67/264 - (25%)
• Similarity: 111/264 - (42%)
• Gaps: 65/264 - (24%)

  Fly   186 SGSEISSPGAPTSA-------SSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNN 243
            :||: .||..|.|:       |:|.|   .:.|........|      |.|:::..|.|.::...
Human    24 AGSK-DSPTLPESSVTDLGYYSAPQH---DYYSGQPYGQTVN------PYTYHHQFNLNGLAGTG 78

  Fly   244 RTSP--------SKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTD 300
            ..||        |...|..:.::| .|||....:...|..|    :...:||.:...|.|.:|:.
Human    79 AYSPKSEYTYGASYRQYGAYREQP-LPAQDPVSVKEEPEAE----VRMVNGKPKKVRKPRTIYSS 138

  Fly   301 FQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQH 365
            :|...|::.:..::|:.:..::|||..|.|::.||||||||||:|.:|..|.|..|      ::|
Human   139 YQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVP------LEH 197

  Fly   366 ---------------------ADYSQLLDAKAKLEPGLHLSHSLAHSMNP----MAAMNIPAMRL 405
                                 :.:|....|:::|.|.|..|.|.::..:|    ..|.|:..
Human   198 SPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSG--- 259

  Fly   406 HPHL 409
             |||
Human   260 -PHL 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeobox	295..347	CDD:278475	21/51 (41%)
DLX3	NP_005211.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39		6/15 (40%)
		DLL_N	27..107	CDD:403572	20/90 (22%)
		COG5576	<109..232	CDD:227863	33/132 (25%)
		homeobox	129..188		23/58 (40%)
		Homeobox	132..186	CDD:395001	21/53 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		14/72 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810