Protein Alignment cad and NKX6-3

DIOPT Version :9

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001351770.1
• Gene: NKX6-3 / 157848
• HGNCID: 26328
• Length: 265
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 61/256 - (23%)
• Similarity: 94/256 - (36%)
• Gaps: 50/256 - (19%)

  Fly   166 APPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVAN-NNNNNNNNNNSPST 229
            :||.....:|.|.|.....:....:::|.....:..||         ||. ...::.....||..
Human    39 SPPGLGPQLAAGTPHGITDILSRPVAAPNNSLLSGYPH---------VAGFGGLSSQGVYYSPQV 94

  Fly   230 HNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKY 294
            .|.:...|......|...:.... ||.........|.|          |||.:.....||.
Human    95 GNFSKAGNEYPTRTRNCWADTGQ-DWRGGRQCSNTPDP----------LSDSIHKKKHTRP---- 144

  Fly   295 RVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQN---KKGSDP 356
              .:|..|...|||.:..::|:....::.||.:|.::|.|||:||||||.|.||::   ...|.|
Human   145 --TFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSALEPSSSTP 207

  Fly   357 NV-----MGVGVQHA-------DYSQLL-----DAKAKLEPGLHLSHSLAHSMNPMAAMNI 400
            ..     .|.|...|       :|::.|     |.|.:|   |...|..|.|:..:.|.::
Human   208 RAPGGAGAGAGGDRAPSENEDDEYNKPLDPDSDDEKIRL---LLRKHRAAFSVLSLGAHSV 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeobox	295..347	CDD:278475	20/51 (39%)
NKX6-3	NP_001351770.1	Homeobox	142..195	CDD:306543	22/58 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810