Protein Alignment cad and Hoxd1

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_034597.2
• Gene: Hoxd1 / 15429
• MGIID: 96201
• Length: 328
• Species: Mus musculus
• Alignment Length: 293
• Identity: 81/293 - (27%)
• Similarity: 115/293 - (39%)
• Gaps: 90/293 - (30%)

  Fly    80 AGEWHSPASSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGGA---PGAPQLNETN 141
            ||...||....|      .|..|...::..:...| |.:|:|..|...||.|   |||     ..
Mouse    70 AGPAQSPVPQPA------APRYAPCTLEGAYERGA-APASAAEYGFLGSGPAFDFPGA-----LG 122

  Fly   142 SSIGVGGA-----------GGG-----GGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEI 190
            .:...|||           |||     |.|..|..|.||..|...::. |:|.|.|..|||
Mouse   123 RAADEGGAHVHYATSAVFSGGGSFLLSGQVDFAAFGEPGPFPACLKEP-ADGHPGPFQTVS---- 182

  Fly   191 SSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDW 255
            .:|||....:||                    .::.|:.|:.                    |:|
Mouse   183 PAPGACPKPASP--------------------TSSLPAAHST--------------------FEW 207

  Fly   256 MKKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRR 320
            ||..          .::|....||:.    |.|......|..::..|..|||||:..::|:|..|
Mouse   208 MKVK----------RNAPKKSKLSEY----GATSPPSAIRTNFSTKQLTELEKEFHFNKYLTRAR 258

  Fly   321 KSELAQTLSLSERQVKIWFQNRRAKERKQNKKG 353
            :.|:|..|.|::.||||||||||.|::|:.::|
Mouse   259 RIEIANCLQLNDTQVKIWFQNRRMKQKKREREG 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	25/54 (46%)
Hoxd1	NP_034597.2	PRK12323	<11..217	CDD:481241	50/213 (23%)
		Antp-type hexapeptide	204..209		2/24 (8%)
		Homeodomain	233..286	CDD:459649	25/52 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..328