Protein Alignment cad and Hoxc4

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_038581.2
• Gene: Hoxc4 / 15423
• MGIID: 96195
• Length: 264
• Species: Mus musculus
• Alignment Length: 279
• Identity: 73/279 - (26%)
• Similarity: 108/279 - (38%)
• Gaps: 92/279 - (32%)

  Fly   108 QHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNH-- 170
            ||||...:.....          .|..|:...:.:|:        .|.|.:...||..|..:|
Mouse    46 QHHHQELYPPPPP----------RPSYPERQYSCTSL--------QGPGNSRAHGPAQAGHHHPE 92

  Fly   171 -QQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNN 234
             .|.:.|  |:|   :||:..|...||.:.|.|   ...|.|:.|:
Mouse    93 KSQPLCE--PAP---LSGTSASPSPAPPACSQP---APDHPSSAAS------------------- 130

  Fly   235 NNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYT 299
                         .:|..:.||||....       :.:||..        .|:.:   :.|..||
Mouse   131 -------------KQPIVYPWMKKIHVS-------TVNPNYN--------GGEPK---RSRTAYT 164

  Fly   300 DFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNK-----------KG 353
            ..|.||||||:..:||:|.||:.|:|.:|.|||||:||||||||.|.:|.::           .|
Mouse   165 RQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAG 229

  Fly   354 SDPNVMGVGV--QHADYSQ 370
            :.|:.:....  ...|:||
Mouse   230 AAPSTLSAATPGTSEDHSQ 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	32/54 (59%)
Hoxc4	NP_038581.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		26/109 (24%)
		Antp-type hexapeptide	135..140		1/4 (25%)
		Homeodomain	157..213	CDD:459649	32/58 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		5/35 (14%)