Protein Alignment cad and Hoxb4

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_034589.3
• Gene: Hoxb4 / 15412
• MGIID: 96185
• Length: 250
• Species: Mus musculus
• Alignment Length: 205
• Identity: 61/205 - (29%)
• Similarity: 83/205 - (40%)
• Gaps: 66/205 - (32%)

  Fly   160 DGGPGSAPPNHQQHIAEGL-PSPPITVSGSEI------------SSPGAPTSASSPHHHLAHHLS 211
            |.||...||........|| |..|:..:...:            |||..|..|.:|.|
Mouse    70 DPGPPPPPPPPPPPPPPGLSPRAPVQPTAGALLPEPGQRSEAVSSSPPPPPCAQNPLH------- 127

  Fly   212 AVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLE 276
                         .|||               .::..:|..:.||:|....       :.:||.
Mouse   128 -------------PSPS---------------HSACKEPVVYPWMRKVHVS-------TVNPNY- 156

  Fly   277 DLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQN 341
                   |.|:.:   :.|..||..|.||||||:..:||:|.||:.|:|..|.|||||:||||||
Mouse   157 -------AGGEPK---RSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQN 211

  Fly   342 RRAKERKQNK 351
            ||.|.:|.:|
Mouse   212 RRMKWKKDHK 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	32/54 (59%)
Hoxb4	NP_034589.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..133		19/97 (20%)
		Antp-type hexapeptide	140..145		1/4 (25%)
		Homeodomain	162..218	CDD:459649	32/58 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..250		1/3 (33%)