Protein Alignment cad and Nkx6-2

DIOPT Version :9

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_899071.2
• Gene: Nkx6-2 / 14912
• MGIID: 1352738
• Length: 277
• Species: Mus musculus
• Alignment Length: 332
• Identity: 75/332 - (22%)
• Similarity: 106/332 - (31%)
• Gaps: 122/332 - (36%)

  Fly    59 AAAHQMYYNSHHMFHSAAAASAGEWHSPA-SSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSAS 122
            ||.|.|......:|..|....|| :.:|| .|.........|             |..:......
Mouse    17 AALHNMAEMKTSLFPYALQGPAG-FKTPALGSLGAQLPLGTP-------------HGISDILGRP 67

  Fly   123 SGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSG 187
            .|::..|.....|:||...||.||             ..||.:|       :|.|.|.|
Mouse    68 VGAAGGGLLGSLPRLNGLASSAGV-------------YFGPAAA-------VARGYPKP------ 106

  Fly   188 SEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPY 252
                              ||.                                     .|.:||.
Mouse   107 ------------------LAE-------------------------------------LPGRPPI 116

  Fly   253 FDWMKKPAYPAQPQPDLSSSPNL---EDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSR 314
            |       :|...|......|.|   .....:||..||   |...|..::..|...|||.:..::
Mouse   117 F-------WPGVVQGSPWRDPRLAGSAQAGGVLDKDGK---KKHSRPTFSGQQIFALEKTFEQTK 171

  Fly   315 YITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQN---------KKGSDPNVMGVGVQHA---- 366
            |:....::.||.:|.::|.|||:||||||.|.||::         |:.||...:.||...|
Mouse   172 YLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDD 236

  Fly   367 DYSQLLD 373
            :|::.||
Mouse   237 EYNRPLD 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeobox	295..347	CDD:278475	20/51 (39%)
Nkx6-2	NP_899071.2	Homeobox	151..205	CDD:395001	20/53 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810