DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment cad and Dlx1

DIOPT Version :9

Sequence 1:NP_001260641.1 Gene:cad / 35341 FlyBaseID:FBgn0000251 Length:445 Species:Drosophila melanogaster
Sequence 2:NP_034183.1 Gene:Dlx1 / 13390 MGIID:94901 Length:255 Species:Mus musculus


Alignment Length:277 Identity:73/277 - (26%)
Similarity:119/277 - (42%) Gaps:57/277 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   176 EGLPSPPITVSGSEISSP-GAPTSASSP----HHHLAHHL--SAVANNNNNNNNNNNSPSTHNNN 233
            |.|.||   |||..:... |.|....||    |.|.:.|.  ||..:..:...::.:|.|.....
Mouse     8 ESLNSP---VSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASSFSRPLGY 69

  Fly   234 NNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLED------LSDLLDA-----SGK 287
            ...||||     |.:..||...::  :||.  ...|:.| .|||      .|.:::.     :||
Mouse    70 PYVNSVS-----SHASSPYISSVQ--SYPG--SASLAQS-RLEDPGADSEKSTVVEGGEVRFNGK 124

  Fly   288 TRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKK 352
            .:...|.|.:|:..|...|.:.:..::|:.:..::|||.:|.|::.||||||||:|:|.:|..|:
Mouse   125 GKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQ 189

  Fly   353 GSDPNVMGVGVQHADYSQLLDAKA------KLEPGLHLSHSLAHSMNPMAAMNIPAMRLHPHLAA 411
            |      |..::.   |.|.:.:|      .:.||.:.:.|........|...:|          
Mouse   190 G------GAALEG---SALANGRALSAGSPPVPPGWNPNSSSGKGSGSSAGSYVP---------- 235

  Fly   412 HSHSLAAVAAHSHQLQQ 428
             |::....:||...:||
Mouse   236 -SYTSWYPSAHQEAMQQ 251

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cadNP_001260641.1 Homeobox 295..347 CDD:278475 20/51 (39%)
Dlx1NP_034183.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..38 11/32 (34%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 95..118 6/23 (26%)
Homeobox 131..185 CDD:395001 20/53 (38%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 204..233 5/28 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0850
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.