Protein Alignment cad and Dbx1

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001005232.1
• Gene: Dbx1 / 13172
• MGIID: 94867
• Length: 335
• Species: Mus musculus
• Alignment Length: 300
• Identity: 82/300 - (27%)
• Similarity: 113/300 - (37%)
• Gaps: 106/300 - (35%)

  Fly   165 SAPPNHQQHIAEGLP----SPP-------ITVSG-SEISSPG-------APTSASSPHHH---LA 207
            |.||.   :::..:|    |||       :..|| |::.|||       :|.:|.||...   |.
Mouse    48 SRPPT---YLSRSIPAASLSPPSQEAPAALADSGTSDLGSPGSGSRRGSSPQTALSPASEPTFLK 109

  Fly   208 HHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSP----SKP------PYFD-----WMK 257
            ..::|:.                       |.:....|||    |.|      |||:     :::
Mouse   110 FGVNAIL-----------------------SSAPRRETSPALLQSPPPKTFAFPYFEGSFQPFIR 151

  Fly   258 KPAYPAQ----PQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITI 318
            ...:||.    |.|...|.|        |.|.||.|.....|.|::|.||..|||.:...:||:.
Mouse   152 SSYFPASSSVVPIPGTFSWP--------LAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISK 208

  Fly   319 RRKSELAQTLSLSERQVKIWFQNRR-----AKERKQNKKG-----------------SDPNVMGV 361
            ..:.:||..|.|.:.||||||||||     :|||:....|                 ||....|.
Mouse   209 PDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGP 273

  Fly   362 GVQHAD-------YSQLLDAKAKLEPGLHLSHSLAHSMNP 394
            |.:..|       |....|.:..||..|..|.  |||.:|
Mouse   274 GDEEEDNPGARLAYHAPADPRHLLEGPLPASP--AHSSSP 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	26/59 (44%)
Dbx1	NP_001005232.1	PRK12323	<49..182	CDD:481241	38/166 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	58..102		13/43 (30%)
		Homeodomain	184..238	CDD:459649	24/53 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..335		18/73 (25%)