DRSC/TRiP Functional Genomics Resources

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Protein Alignment cad and Dr

DIOPT Version :10

Sequence 1:NP_001260641.1 Gene:cad / 35341 FlyBaseID:FBgn0000251 Length:445 Species:Drosophila melanogaster
Sequence 2:XP_313452.5 Gene:Dr / 1274345 VectorBaseID:AGAMI1_005699 Length:386 Species:Anopheles gambiae


Alignment Length:456 Identity:94/456 - (20%)
Similarity:144/456 - (31%) Gaps:153/456 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 TLPYTQKHSA--ANLAYASAAGQPWNWTPNYHH-------------TPPNHQFLGDVDSSHAAHH 57
            |:|..||.::  :|.:.||........|||.||             |||:...|..:......|.
Mosquito    20 TVPMQQKSNSRISNFSVASLLADTRPKTPNAHHAIITSGTPTTTTPTPPSLTPLSPLMVHGPPHG 84

  Fly    58 AAAAHQMYYN---------------SHHMFHSAAAASAGEWHSPASSTADNFVQNVPT-----SA 102
            ||..||....               |..|..:..::......||.|....:.::|:..     :.
Mosquito    85 AALLHQAMTTALTTVTTTTLPGTSPSSDMLPANLSSHTTSSSSPRSQHDGSSLRNLDADRHTDTP 149

  Fly   103 HQLMQQHHHHHAH----------------ASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGG 151
            |.|::...:...|                .|.|.:..|.....|:||:|      |::|:   |.
Mosquito   150 HSLLESDDYDSNHDEEEDSIVDIEDMDQELSESGSQPGGRKGSGSPGSP------SAMGM---GH 205

  Fly   152 GGGVGGATDGGPGSAP--PNHQQHIAE----------GLPSPPITVSGSEISSPGAPTSASSPHH 204
            |...|.|.....|..|  |.....:|.          |:|.|     |:....|..|........
Mosquito   206 GSPPGAALAAAAGHVPIRPTPFSALAAAAAAWGGMSGGVPWP-----GARQMPPFGPPGLFPGQG 265

  Fly   205 HLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDL 269
            ..|..|          ..:|..|...         .|..:..|::.|                  
Mosquito   266 FGAGQL----------GGDNEPPRIK---------CNLRKHKPNRKP------------------ 293

  Fly   270 SSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQ 334
                                     |..:|..|.|.|||::...:|::|..::|.:.:|.|:|.|
Mosquito   294 -------------------------RTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQ 333

  Fly   335 VKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKAKLEPGLHLSHSLAHSMNPMAAMN 399
            |||||||||||.::              :|.|:..::..|.....||..|.....|......||:
Mosquito   334 VKIWFQNRRAKAKR--------------LQEAELEKIKMAALGRAPGAQLYMGYFHPSLMGGAMH 384

  Fly   400 I 400
            :
Mosquito   385 L 385

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cadNP_001260641.1 Homeodomain 293..348 CDD:459649 25/54 (46%)
DrXP_313452.5 None

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