Protein Alignment cad and Rax

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_446130.1
• Gene: Rax / 114213
• RGDID: 620371
• Length: 342
• Species: Rattus norvegicus
• Alignment Length: 279
• Identity: 67/279 - (24%)
• Similarity: 109/279 - (39%)
• Gaps: 69/279 - (24%)

  Fly   163 PGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSP 227
            ||..|.     :|:|    ..:::|..:.|||..||.       .|.:.|:......:...:..|
  Rat     4 PGCPPA-----MADG----SFSLAGHLLRSPGGSTSR-------LHSIEAILGFTKEDGILDTFP 52

  Fly   228 STHNNNNNNN--------------SVSNNNRTSPSKP---PYFDWMKKPAYP-----AQPQPDLS 270
            :..::..:..              ....:..:.|:.|   |.|: ..:|.||     |:|.|.|.
  Rat    53 AERSSRGSKERDPRLGARSACPKAPAGGSESSPPAAPGLVPEFE-ATRPCYPKEQGEARPSPGLP 116

  Fly   271 SSPNLEDLSDLLDASGKTRTKD-KYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQ 334
            ..|...| |.|.:.....:.|. :.|..:|.:|..|||:.:..|.|..:..:.|||..::|.|.:
  Rat   117 VGPAAGD-SKLSEEEEPPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVR 180

  Fly   335 VKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKAKLEPGLHLSHSLAHSMNPMAAMN 399
            |::||||||||.|:|.|                   |..:..||:....||.|.:...:.:|.:.
  Rat   181 VQVWFQNRRAKWRRQEK-------------------LEVSSMKLQDSPLLSFSRSPPSSALAPLG 226

  Fly   400 IP---------AMRLHPHL 409
            .|         |:.|.|.|
  Rat   227 GPGSGSGPPGSALPLEPWL 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	22/54 (41%)
Rax	NP_446130.1	Octapeptide motif	33..40		2/6 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	49..141		17/93 (18%)
		Homeodomain	138..194	CDD:459649	22/55 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..295		9/37 (24%)
		OAR	316..331	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	319..332
		Nuclear localization signal. /evidence=ECO:0000255	325..329