Protein Alignment cad and Hoxa11

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001123350.1
• Gene: Hoxa11 / 103692131
• RGDID: 1564605
• Length: 313
• Species: Rattus norvegicus
• Alignment Length: 367
• Identity: 86/367 - (23%)
• Similarity: 120/367 - (32%)
• Gaps: 152/367 - (41%)

  Fly     6 YNTLPYTQKHSAANLAYA---------------SAAGQPWNWTPNYHHTPPNHQFLGDVDSSHAA 55
            |...|.|:.|...|||:.               ||||.|                 |||
  Rat    66 YAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPSAAGVP-----------------GDV------ 107

  Fly    56 HHAAAAHQMYYNSHHMFHSAAAASAGEWHSPASSTADNFVQNV------PTSAHQLMQQHHHHHA 114
                               .|.:||..:|.|..:.:.||...|      |.:..|..:..:....
  Rat   108 -------------------LAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPE 153

  Fly   115 HASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLP 179
            :.:||......::..|.|.|    ...|:..|..|..|.....::|||.|.   ..|:..||
  Rat   154 NLASSDYPGDKNAEKGPPTA----AATSAAAVAAAATGAPATSSSDGGGGG---GCQEAAAE--- 208

  Fly   180 SPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNR 244
                     |......|.|:|||.
  Rat   209 ---------EKERRRRPESSSSPE----------------------------------------- 223

  Fly   245 TSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKE 309
                                     |||.:.||.:   ..||..||:.| |..||.:|..|||:|
  Rat   224 -------------------------SSSGHTEDKA---GGSGGQRTRKK-RCPYTKYQIRELERE 259

  Fly   310 YCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNK 351
            :..|.||...::.:|::.|:|::|||||||||||.||:|.|:
  Rat   260 FFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINR 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	28/54 (52%)
Hoxa11	NP_001123350.1	DUF3528	26..154	CDD:432284	25/129 (19%)
		Homeodomain	242..298	CDD:459649	28/56 (50%)