Protein Alignment cad and evx2

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: XP_002935724.3
• Gene: evx2 / 100498260
• XenbaseID: XB-GENE-852923
• Length: 502
• Species: Xenopus tropicalis
• Alignment Length: 368
• Identity: 80/368 - (21%)
• Similarity: 134/368 - (36%)
• Gaps: 100/368 - (27%)

  Fly    84 HSPASSTADNFVQNVPT----SAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLN---ETN 141
            |||.|.      :.:||    :.:.:::...|.| ||...|....|||..||.|.....   |..
 Frog    96 HSPGSG------KRLPTVSDPAGNAVLEALEHAH-HAGRLSPRITSSSLHGAIGEHHSKGKFEIE 153

  Fly   142 SSIGVGGA--GGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHH 204
            |..|:..:  ...|.:.||..|...|..|...:   |...:..:.|..:.:.|||
 Frog   154 SLFGISHSTEESNGDISGADRGKKLSQYPEVSK---EADMNSDVEVGCAGLRSPG---------- 205

  Fly   205 HLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDL 269
                            :.|.|.....:.::.::..|....::||                   .:
 Frog   206 ----------------SINGNQLKESSKDSGSSVASTTGSSTPS-------------------GI 235

  Fly   270 SSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQ 334
            .|...|..:.....|:.:.|   :||..:|..|...||||:....|::..|:.|||..|:|.|..
 Frog   236 GSLNGLNPVGSSSSAADQVR---RYRTAFTREQIGRLEKEFYRENYVSRPRRCELAAALNLPETT 297

  Fly   335 VKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKAKLEPGLH---LSHSLAHSMNPMA 396
            :|:||||||.|:::|....|.|:                   ..:|..:   ::|:.|....|..
 Frog   298 IKVWFQNRRMKDKRQRLAMSWPH-------------------PADPSFYTYMMTHAAATGSLPYP 343

  Fly   397 AMNIPAMRLHPHLAAHSHSLAAVAAHSHQLQQQHSAQMSAAAA 439
            ..:...:..:||:...:.:.||.|:.:           :||||
 Frog   344 FHSHVPLHYYPHVGVTAAAAAAAASGA-----------AAAAA 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	24/54 (44%)
evx2	XP_002935724.3	Homeodomain	255..311	CDD:459649	25/58 (43%)