Protein Alignment cad and alx4

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: XP_004913406.1
• Gene: alx4 / 100493396
• XenbaseID: XB-GENE-853003
• Length: 376
• Species: Xenopus tropicalis
• Alignment Length: 281
• Identity: 61/281 - (21%)
• Similarity: 105/281 - (37%)
• Gaps: 65/281 - (23%)

  Fly   214 ANNNNNNNNNNNSPSTHNNNNNNNSVSNNN---RTSPSKPPYFDWMKKPAYPAQP-----QPDLS 270
            ||..:|:.....|.:.:..::.::....::   :::|.|.| .|.:|....|..|     ..:.:
 Frog    71 ANVQSNSGEQQGSFTKYQAHHPSHQQQQSHLYMQSTPCKSP-SDSLKVQDSPGDPLIPCYAKESA 134

  Fly   271 SSPNLE-------------------------DL-SDLLDASGKTRTKDKYRVVYTDFQRLELEKE 309
            .:||.:                         || .|..::......|.:.|..:|.:|..||||.
 Frog   135 LTPNSDHQGMDSGYITSKETAGKGSQDRGSGDLPMDKTESESNKGKKRRNRTTFTSYQLEELEKV 199

  Fly   310 YCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDA 374
            :..:.|..:..:.:||....|:|.:|::||||||||.||:.:.|....|      ...:|...:.
 Frog   200 FQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQV------RTHFSSAYEL 258

  Fly   375 KAKLEPGLHLSHSLAHSMNPMAAMN------IPAM-------------RLHPHLAAHSHSLAAVA 420
                 |.|..:.:.|...||....|      :||.             ..|||.|.......:|.
 Frog   259 -----PLLTRAENYAQIQNPSWIGNNGGGSPVPACVVPCDTVSSCMSPHSHPHSAGGVSEFLSVP 318

  Fly   421 AHSHQLQQQHSAQMSAAAAVG 441
            .....:.|.|...:..:||:|
 Frog   319 GPGAHVGQTHMGGLFGSAAMG 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	21/54 (39%)
alx4	XP_004913406.1	COG5576	120..266	CDD:227863	36/156 (23%)
		Homeodomain	182..238	CDD:459649	21/55 (38%)
		OAR	352..370	CDD:461067