Protein Alignment cad and nkx2-3

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: XP_002937234.1
• Gene: nkx2-3 / 100486189
• XenbaseID: XB-GENE-852996
• Length: 328
• Species: Xenopus tropicalis
• Alignment Length: 239
• Identity: 59/239 - (24%)
• Similarity: 91/239 - (38%)
• Gaps: 59/239 - (24%)

  Fly   263 AQPQPDLSSSPNL-----------EDLSDLLDASG----------------------KTRTKDKY 294
            |:|..|:..||:.           |:..|.|...|                      |.|::.|.
 Frog    85 AEPHGDVGLSPDRYVALRDPKEEDEEEEDSLREGGNKSCFLNKSPDGEGKLEDPDRPKQRSRRKP 149

  Fly   295 RVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGS----- 354
            ||:::..|..|||:.:...||::...:..||.:|.|:..||||||||||.|.::|.:..|
 Frog   150 RVLFSQAQVFELERRFKQQRYLSAPEREHLANSLKLTSTQVKIWFQNRRYKCKRQRQDKSLEMGT 214

  Fly   355 ----DPNVMGVGVQHADYSQLLDAKAKLEPGLHLSHS-------LAHSMNPMAAMN--------- 399
                .|..:.|.|...|....:..........:::.|       .|:|.|...:.|
 Frog   215 HHPPPPRRVAVPVLVRDGKPCIGGSQSYNTAYNVTASPYSYNSYPAYSYNNSPSYNTNYNCNYAS 279

  Fly   400 IPAMRLHPHLAAHSHSLAAVAAHSHQLQQQHSAQMSAAAAVGTL 443
            ||: .||....:...:|..::..|:..|.|.....|..|..|||
 Frog   280 IPS-NLHNTGTSPFVNLGNLSQISNSPQPQTHPGTSVPACQGTL 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	24/54 (44%)
nkx2-3	XP_002937234.1	Homeodomain	147..203	CDD:459649	24/55 (44%)