Protein Alignment cad and shox2

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001093694.1
• Gene: shox2 / 100101703
• XenbaseID: XB-GENE-480993
• Length: 311
• Species: Xenopus tropicalis
• Alignment Length: 339
• Identity: 80/339 - (23%)
• Similarity: 118/339 - (34%)
• Gaps: 136/339 - (40%)

  Fly   141 NSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHH 205
            |..|| ||.|||||.|||..                  |...:.:|...|...|:|
 Frog    53 NRCIG-GGGGGGGGGGGARS------------------PVLELDLSVERIRESGSP--------- 89

  Fly   206 LAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLS 270
               .|:.|                                ||......:.:|:.|
 Frog    90 ---KLTEV--------------------------------SPEIKERKEELKQQA---------- 109

  Fly   271 SSPNLEDLSDLLDASGKTRTKD-KYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQ 334
                       |:..|:|:.|. :.|..:|..|..|||:.:..:.|.....:.||:|.|.|||.:
 Frog   110 -----------LEEEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEAR 163

  Fly   335 VKIWFQNRRAKERKQNKKGSDPNVMGVGVQ-----------------------HADYSQLLDAKA 376
            |::||||||||.|||..:.....::|.|.|                       |.:...|   ..
 Frog   164 VQVWFQNRRAKCRKQENQLHKGVLIGAGSQFEACRVAPYVNVGALRMPFQQDSHCNVPSL---SF 225

  Fly   377 KLEPGLHLSHSLAHSMNPMAAMNIPAMRLHPHLAAHSH-----------SLAAVAAHSHQLQQQH 430
            :::..|.|..::||:.:          .|||||.||:.           .||.:||.:    ...
 Frog   226 QVQAQLQLDSAVAHAHH----------HLHPHLTAHAPYMMFPAPPFGLPLATLAAET----ATA 276

  Fly   431 SAQMSAAAAVGTLS 444
            ::.::||||..|.|
 Frog   277 ASVVAAAAAAKTSS 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	23/54 (43%)
shox2	NP_001093694.1	Homeodomain	121..177	CDD:459649	23/55 (42%)
		OAR	292..307	CDD:461067