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Protein Alignment dia and FH4

DIOPT Version :9

Sequence 1:	NP_001246113.1	Gene:	dia / 35340	FlyBaseID:	FBgn0011202	Length:	1098	Species:	Drosophila melanogaster
Sequence 2:	NP_001319073.1	Gene:	FH4 / 839028	AraportID:	AT1G24150	Length:	763	Species:	Arabidopsis thaliana

Alignment Length:	686	Identity:	164/686 - (23%)
Similarity:	256/686 - (37%)	Gaps:	166/686 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   452 LLLD----DIVEKAKAKESKRSEE---YEKKI-----EQLESAKQEAEAKAAHLEEKVKLM---- 500
            |:||    |::...|.::|:|..:   :.|:|     |:......:::.|:..:.|...|.
plant   143 LILDENGLDVLYWRKLQQSQRDNKGGSFRKEIIHGDDEEKNVIYSKSKKKSGPVTETPLLRGRSS 207

  Fly   501 ----------EANGVAAPSPN-KLPKVNIPMPPPPPGGGGAPPPPPPPMPGRAGGGPPPPPPPPM 554
                      ..|......|: |........|.|.|     |||||||:|.:....|||||||.:
plant   208 TSHSVIHNDNYRNATTTHPPHVKTDSFEFVKPDPTP-----PPPPPPPIPVKQSATPPPPPPPKL 267

  Fly   555 PGRAGGPPPPPPPPGMGGPPPPPMPGMMRPGGGPPPPPMMMGPMVPVLPHG---LKPKKKWDVKN 616
              :..||.|||       |||......:.......|||...|.......:|   ||| ..||..|
plant   268 --KNNGPSPPP-------PPPLKKTAALSSSASKKPPPAPRGSSSGESSNGQVKLKP-LHWDKVN 322

  Fly   617 PMKRANWKAIVPAKMSDKAF-WVKCQEDKLAQDDFLAELAVKFSSKPVKKEQKDAVD-KPTTLTK 679
            |             .||.:. |.|......:.|..|.|....:.:.. ||...|..| ||::.:.
plant   323 P-------------DSDHSMVWDKIDRGSFSFDGDLMEALFGYVAVG-KKSPDDGGDKKPSSASP 373

  Fly   680 KNVDLRVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILSSNILQQLIQYLPP-----PE 739
              ..:.:||.:.:||.||:    ||.|...:                  .:|::.|..     |:
plant   374 --AQIFILDPRKSQNTAIV----LKSLGMTR------------------DELVESLMEGHDFHPD 414

  Fly   740 HLKRLQEIKAKGEPLPPIEQFAATIGEIKRLS-----------------PRLHNLNFKLTYADMV 787
            .|:||..|....|....|.||.   |:.|.|:                 .||:.|.|:..|...:
plant   415 TLERLSRIAPTKEEQSAILQFD---GDTKMLADAESFLFHLLKAVPCAFTRLNALLFRANYYPEI 476

  Fly   788 QDIKPDIVAGTAACEEIRNSKKFSKILELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKDADN 852
            .:...::.....||.|:|:...|.|:||.||..||.||:|:....|..|.::.|.|||:.|..|.
plant   477 SNHNKNLQTLDLACTELRSRGLFVKLLEAILKSGNRMNAGTARXDAQAFNLTALLKLSDVKSVDG 541

  Fly   853 KQTLLHYLADLV-----------------------------------EKKF-----PDALNFYDD 877
            |.|||:::.:.|                                   ||::     |.......:
plant   542 KTTLLNFVVEEVVRSEGKRCVLNRRTNRSFSRSSSSSISEVISKEEQEKEYLRLGLPVVGGLSSE 606

  Fly   878 LSHVNKASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQCDDDKFSEVMGKFAEECRQQVDVLG 942
            .::|.||:.|:.|.:......:.|..|:....|..::....:..:|.:.|.:|.:...::|.:..
plant   607 FTNVKKAAAVDYDTVAATCLALTSRAKDARRVLAQSEGDNKEGVRFVKKMNEFLDSVEEEVKLAK 671

  Fly   943 KMQLQMEKLYKDLSEYYAFDPSK-YTMEEFFADIKTFKDAFQAAHNDNVRVREELEKKRRLQEAR 1006
            :.:.::.:|.|..:|||.....| ......|..::.|     .|..|.|.|    |..|.||  |
plant   672 EEEKKVLELVKRTTEYYQAGAVKGKNPLHLFVIVRDF-----LAMVDKVCV----EIARNLQ--R 725

  Fly  1007 EQSAREQQERQQRKKAVVD----MDAPQTQEGVMDS 1038
            ..|....|:|...|..|:.    .|..::..|..||
plant   726 RSSMGSTQQRNAVKFPVLPPNFMSDRSRSDSGGSDS 761

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.