DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dia and AT5G07770

DIOPT Version :9

Sequence 1:	NP_001246113.1	Gene:	dia / 35340	FlyBaseID:	FBgn0011202	Length:	1098	Species:	Drosophila melanogaster
Sequence 2:	NP_001332695.1	Gene:	AT5G07770 / 830670	AraportID:	AT5G07770	Length:	729	Species:	Arabidopsis thaliana

Alignment Length:	603	Identity:	143/603 - (23%)
Similarity:	238/603 - (39%)	Gaps:	145/603 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   502 ANGVAAPSPNKLPKVNIPMPPPPPGGGGAPP-----PPPPPMPGRAGGGPPPPPPPPM------- 554
            |:.|..|.    .:..:|:|||||     ||     |.||||.||.   |||||||||
plant    16 ADAVVTPP----MRGRVPLPPPPP-----PPMRRSAPSPPPMSGRV---PPPPPPPPMFDPKGAG 68

  Fly   555 -------PG---------------------------------------------------RAGG- 560
                   ||                                                   ::|.
plant    69 RVICCLRPGQNKSSLKRFQCGKLTNAWEELQRHGEAQTAPEFDLSEIEALFSAAVQNQADKSGSR 133

  Fly   561 -----------------------PPPPPPPPGMGGPPPPPMPGMMRPGGGPPPPPMMMGPMVPVL 602
                                   ||||||.|....|||||........|.    .|:.|...||.
plant   134 REAFEANPDKLQLISGADALVPLPPPPPPMPRRSPPPPPPRFDAFDHKGA----RMVCGFRCPVT 194

  Fly   603 PHGLKPKKKWDVKNPMKRANWKAIVPAKMSDKAFWVKCQ----EDKLAQDDFLAELAVKFS--SK 661
            .           ::.:|..:|..|..|...  :.|.:.|    |.:.|.:..:.|:...||  :|
plant   195 K-----------RSSLKPLHWVKITRALQG--SLWDELQIQYGESQTAIELDVPEIETLFSVGAK 246

  Fly   662 PVKKEQKDAVDKPTTLTKKNVDLRVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILSSN 726
            |..|.:.:.|.             ::|.|.|.|..:.|  .:..:....:...::..|..:|..:
plant   247 PRPKPKPEKVP-------------LIDLKRANNTIVNL--KILKMPLPDMMAAVMAMDESVLDVD 296

  Fly   727 ILQQLIQYLPPPEHLKRLQEIKAKGEPLPPIEQFAATIGEIKRLSPRLHNLNFKLTYADMVQDIK 791
            .::.|||..|..|.::.|:........|...||....:.::.|...:|..|:||:.:...:...:
plant   297 QIENLIQLCPTKEEMELLKNYTGDKATLGKSEQCLLELMKVPRFEAKLRVLSFKIPFGTKITKFR 361

  Fly   792 PDIVAGTAACEEIRNSKKFSKILELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTL 856
            ..:....:||||:|:|:...:|:::||.|||.:|.|:...:|.||.:..|..||.|:..:||.||
plant   362 KMLNVVNSACEEVRSSQMLKEIMKIILFLGNTLNQGTARGSAVGFRLDSLLILSETRADNNKMTL 426

  Fly   857 LHYLADLVEKKFPDALNFYDDLSHVNKASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQCDDD 921
            :|||..::..|..|.|:|:.||..:.....:|:.::.:.:..:...::.|:.:|..::.......
plant   427 MHYLCKVLASKAADLLDFHKDLQSLESTLEINLKSLAEEIHAITKGLEKLKQELTASETDGPVSQ 491

  Fly   922 KFSEVMGKFAEECRQQVDVLGKMQLQMEKLYKDLSEYYAFDPSKYTMEEFFADIKTFKDAFQAAH 986
            .|.:::..|......||..:..:..........|:.|:..||:.|..|:..|.:.:|...|:.||
plant   492 VFRKLLKDFISSAETQVATVSTLYSSARINADALAHYFGEDPNHYPFEKVSATLLSFIRLFKKAH 556

  Fly   987 NDNVRVREELEKKRRLQE 1004
            .:||: :|:||||:...|
plant   557 QENVK-QEDLEKKKAATE 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dia	NP_001246113.1	Drf_GBD	66..248	CDD:283920
		Drf_FH3	253..453	CDD:283917
		FH2	608..983	CDD:280362	85/380 (22%)
AT5G07770	NP_001332695.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	1	1.000	-	-		FOG0000085
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920