DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dia and AT2G43800

DIOPT Version :9

Sequence 1:	NP_001246113.1	Gene:	dia / 35340	FlyBaseID:	FBgn0011202	Length:	1098	Species:	Drosophila melanogaster
Sequence 2:	NP_181908.1	Gene:	AT2G43800 / 818984	AraportID:	AT2G43800	Length:	894	Species:	Arabidopsis thaliana

Alignment Length:	581	Identity:	128/581 - (22%)
Similarity:	232/581 - (39%)	Gaps:	131/581 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   481 SAKQEAEAKAAHLEE-KVKLMEANGVAAPSP-NKLPKVNIPMPPPPPGGGGAPPPPPPPMPGR-- 541
            |.::::..:.:.::: ..:.:..:|..:.|| |..|.:|     ..||....|....||:...
plant   334 SGRKQSPTRVSDVDQIDNRSINGSGSNSCSPTNFAPSLN-----ASPGTSLKPKSISPPVSLHSQ 393

  Fly   542 --AGGGPPPPPPPPMPGRAGGPPPPPPPPGMGGPPPPPMPGMMRPGGGPPPPPMMMGPMVPVLPH 604
              :..|.|....|..|     ||||||||.:...|                         ..:.|
plant   394 ISSNNGIPKRLCPARP-----PPPPPPPPQVSEVP-------------------------ATMSH 428

  Fly   605 GL-----KPKKKWDVKNP-MKRANWKAIVPAKMSDKAFWVKCQEDKLAQDDFLAELAVKFSSKPV 663
            .|     .|:||.:...| :|..:|.. |.|..|....|.:.:.:....::.:.|...|
plant   429 SLPGDDSDPEKKVETMKPKLKTLHWDK-VRASSSRVMVWDQIKSNSFQVNEEMIETLFK------ 486

  Fly   664 KKEQKDAVDKPTTLTKKNV------DLRVLDSKTAQNLAIMLGGSLKHLSYEQIKIC--LLRCDT 720
                   |:.||:.|:..|      :.|.||.:.:.|:||:    |:.|:....::|  |:..::
plant   487 -------VNDPTSRTRDGVVQSVSQENRFLDPRKSHNIAIL----LRALNVTADEVCEALIEGNS 540

  Fly   721 DILSSNILQQLIQYLPPPEHLKRLQEIKAKGEPLP----PIEQFAATIGEI----KRLSPRLHNL 777
            |.|...:|:.|::..|..|...:|:|:|...:..|    |.|:|...:..|    ||:...|:.:
plant   541 DTLGPELLECLLKMAPTKEEEDKLKELKDDDDGSPSKIGPAEKFLKALLNIPFAFKRIDAMLYIV 605

  Fly   778 NF--KLTYADMVQDIKPDIVAGTAACEEIRNSKKFSKILELILLLGNYMNSGSKNEAAFGFEISY 840
            .|  ::.|.:...|..      .||..|::|::.|.|:||.:|..||.||.|:....|..|::..
plant   606 KFESEIEYLNRSFDTL------EAATGELKNTRMFLKLLEAVLKTGNRMNIGTNRGDAHAFKLDT 664

  Fly   841 LTKLSNTKDADNKQTLLHYLADLVEK-----------------KFPDALNFYDDLS--------- 879
            |.||.:.|.||.|.||||::...:.|                 ...:...|.|||.
plant   665 LLKLVDIKGADGKTTLLHFVVQEIIKFEGARVPFTPSQSHIGDNMAEQSAFQDDLELKKLGLQVV 729

  Fly   880 --------HVNKASRVNMDAIQKAMRQMN---SAVKNLETDLQNNKVPQCDDDKFSEVMGKFAEE 933
                    :|.||:.::.:::.....::.   :.||.:.|:|:.    :...::|.|.|..|..:
plant   730 SGLSSQLINVKKAAAMDSNSLINETAEIARGIAKVKEVITELKQ----ETGVERFLESMNSFLNK 790

  Fly   934 CRQQVDVLGKMQLQMEKLYKDLSEYYAFDPSKYTMEEFFADIKTFKDAFQAAHNDNVRVRE 994
            ..:::..|......:.|:.|:::||:..:...:.. ..||.::.|.........:..||.|
plant   791 GEKEITELQSHGDNVMKMVKEVTEYFHGNSETHPF-RIFAVVRDFLTILDQVCKEVGRVNE 850

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dia	NP_001246113.1	Drf_GBD	66..248	CDD:283920
		Drf_FH3	253..453	CDD:283917
		FH2	608..983	CDD:280362	98/430 (23%)
AT2G43800	NP_181908.1	FH2	438..839	CDD:396655	97/429 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I2015
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X420
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.970