DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dia and inf2

DIOPT Version :9

Sequence 1:	NP_001246113.1	Gene:	dia / 35340	FlyBaseID:	FBgn0011202	Length:	1098	Species:	Drosophila melanogaster
Sequence 2:	XP_021322927.1	Gene:	inf2 / 792715	ZFINID:	ZDB-GENE-140711-5	Length:	238	Species:	Danio rerio

Alignment Length:	186	Identity:	41/186 - (22%)
Similarity:	83/186 - (44%)	Gaps:	13/186 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 LRVALTSNPISWIKEF-GVAGIG----TIEKLLARSKNNASYEKIEFEAIRCLKAIMNNTWGLNV 211
            ||..|..:..:|:.:| .::|:.    .:::|..|..:..:...::...:.|::|:||::.|::.
Zfish    57 LRKRLEGSEEAWMVQFLELSGLDLLLEALDRLSGRGCSRIADALLQLTCVSCVRAVMNSSAGIHF 121

  Fly   212 VLNPDQHSVVLLLAQSLDPRKPQTMCEALKLLASFCIVYERNGYEKVLRAITTIAATSFKASERF 276
            ::  |....|..|:|:||........:..:|||:.. ::...|:...|.|:........: ..||
Zfish   122 IV--DNEGYVRKLSQALDTSNTMVKKQVFELLAALS-MFSSEGHRLALDALEHYKCVKTQ-QYRF 182

  Fly   277 RPIVDALFASDQQDPKRDLACHSLIFINTLTNTPTDLNFRLHLRCEIMRMGLYDRL 332
            ..|::.|.::|.......|    |..||.|..:...|..|..:|.|.:.:.|...|
Zfish   183 SVIMNELRSTDNVPYMVTL----LSVINALIFSADGLQQRDKMRKEFIGLQLLQLL 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dia	NP_001246113.1	Drf_GBD	66..248	CDD:283920	22/100 (22%)
		Drf_FH3	253..453	CDD:283917	19/80 (24%)
		FH2	608..983	CDD:280362
inf2	XP_021322927.1	Drf_GBD	<98..154	CDD:310750	14/57 (25%)
inf2	XP_021322927.1	Drf_FH3	160..>226	CDD:310747	17/70 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010