DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dia and AT5G07740

DIOPT Version :9

Sequence 1:	NP_001246113.1	Gene:	dia / 35340	FlyBaseID:	FBgn0011202	Length:	1098	Species:	Drosophila melanogaster
Sequence 2:	NP_001331227.1	Gene:	AT5G07740 / 3770686	AraportID:	AT5G07740	Length:	1683	Species:	Arabidopsis thaliana

Alignment Length:	579	Identity:	171/579 - (29%)
Similarity:	271/579 - (46%)	Gaps:	83/579 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   504 GVAAPSPNKLPKVNIPMPPPPPGGGGAPPPPPPPMPGRA---------GGGPP----------PP 549
            |.|.|.|....:...|.|||||..|||||||||||.|.|         ||.||          ||
plant  1105 GGAQPPPPPPMRGGAPPPPPPPMRGGAPPPPPPPMRGGAPPPPPPPMHGGAPPPPPPPMRGGAPP 1169

  Fly   550 PPPPMPGRAGGPPPPPPPPGMGGPPPPPMPGMMRPGGGPPPPPMMMGPMVPVLPHGL-----KPK 609
            ||||..||..|.||||||||...|.|||.||...||||||||||:......|.|.|.     .|:
plant  1170 PPPPPGGRGPGAPPPPPPPGGRAPGPPPPPGPRPPGGGPPPPPMLGARGAAVDPRGAGRGRGLPR 1234

  Fly   610 KKW----DVKNPMKRANWKAIVPAKMSDKAFWVKCQ---EDKLAQDDFLAELAVKFSS---KPVK 664
            ..:    ..|:.:|..:|..:..|...  :.|.:.|   |.:...:..::|:...||:   ||..
plant  1235 PGFGSAAQKKSSLKPLHWVKVTRALQG--SLWDELQRHGESQTPSEFDVSEIETLFSATVQKPAD 1297

  Fly   665 K---EQKDAVDKPTTLTKKNVDLRVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILSSN 726
            |   .:|....||.       .::::|.:.|.|..|||  :...:....:...:|..|..:|..:
plant  1298 KSGSRRKSVGAKPE-------KVQLIDLRRANNTEIML--TKVKMPLPDMMAAVLAMDESVLDVD 1353

  Fly   727 ILQQLIQYLPPPEHLKRLQEIKAKGEPLPPIEQFAATIGEIKRLSPRLHNLNFKLTYADMV---- 787
            .::.||::.|..|.::.|:........|...||:...:.::.|:..:|...:||..:...|
plant  1354 QIENLIKFCPTKEEMELLKNYTGDKTTLGKCEQYFLELMKVPRVEAKLRVFSFKFQFGTQVWWNY 1418

  Fly   788 ------------------------------QDIKPDIVAGTAACEEIRNSKKFSKILELILLLGN 822
                                          .:.|..:.|..:||||:|:|:|..:|::.||.|||
plant  1419 LIPLFSVYLILWRTKYNFIRLLIMMFFVQITEFKKSLNAVNSACEEVRSSQKLKEIMKKILYLGN 1483

  Fly   823 YMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTLLHYLADLVEKKFPDALNFYDDLSHVNKASRV 887
            .:|.|:...||.||::..|:|||:|:.|::|.||:|||..::..|....|:|..||..:..||::
plant  1484 TLNQGTARGAAVGFKLDSLSKLSDTRAANSKMTLMHYLCKVLASKASVLLDFPKDLESLESASKI 1548

  Fly   888 NMDAIQKAMRQMNSAVKNLETDLQNNKVPQCDDDKFSEVMGKFAEECRQQVDVLGKMQLQMEKLY 952
            .:.::.:.|:.:...::.|..:|..::......|.|.:.:|.|......:|..:..:...:.:..
plant  1549 QLKSLAEEMQAIIKGLEKLNQELTASESDGPVSDVFRKTLGDFISVAETEVATVSSLYSVVGRNA 1613

  Fly   953 KDLSEYYAFDPSKYTMEEFFADIKTFKDAFQAAHNDNVRVREELEKKRRLQEAREQSAR 1011
            ..|:.|:..||::...|:..|.:..|...|:.||.:||: :.|||||:.|:||..:.|:
plant  1614 DALAHYFGEDPNRCPFEQVTATLLNFIRLFKKAHEENVK-QAELEKKKALKEAEMEKAK 1671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dia	NP_001246113.1	Drf_GBD	66..248	CDD:283920
		Drf_FH3	253..453	CDD:283917
		FH2	608..983	CDD:280362	94/421 (22%)
AT5G07740	NP_001331227.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	1	1.000	-	-		FOG0000085
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920