Protein Alignment dia and Fhdc1

DIOPT Version :9

• Sequence 1: NP_001246113.1
• Gene: dia / 35340
• FlyBaseID: FBgn0011202
• Length: 1098
• Species: Drosophila melanogaster
• Sequence 2: NP_001099907.1
• Gene: Fhdc1 / 295161
• RGDID: 1311955
• Length: 1148
• Species: Rattus norvegicus
• Alignment Length: 642
• Identity: 158/642 - (24%)
• Similarity: 262/642 - (40%)
• Gaps: 127/642 - (19%)

  Fly   504 GVAAPSPNKLPKVNIPMPPPPPGGGGAPPPPPPPMPGRAGGGPPPPPPPPMPGRAGGPPPPPPPP 568
            |..:||.:         |.|||     |||||||.|....|.||.||||..|...||||.|||||
  Rat    27 GQTSPSAS---------PAPPP-----PPPPPPPCPHSGEGFPPSPPPPLPPPLPGGPPVPPPPP 77

  Fly   569 GMGGPPPPPMPGMMRPGGGPPPPPMMMGPMVPVLPHGLKPKKKWDVKNPMKRANWKAIVPAKMSD 633
            |:  ||...:.|....|                       |||     .|:...||.|...::..
  Rat    78 GL--PPASYLNGYSSLG-----------------------KKK-----RMRSFFWKTIPEEQVRG 112

  Fly   634 KA-FWV-------------KCQEDKLAQDDFLAELAVKFSSKPVKKEQKDAVDKPTTLTKKNVDL 684
            |. .|.             |..|:...|.:..::.::......:....:||.:          ::
  Rat   113 KTNIWTLAAKQQHHYQIDKKTIEELFGQQEDTSKASLPKRGGALNSSFRDARE----------EI 167

  Fly   685 RVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILSSNILQQLIQYLPPPEHLKRLQEIKA 749
            .|||:|.:.|:.|.|....|  |.:.|...:.:..::...|..|:::::.||..|.:|:|:....
  Rat   168 AVLDAKRSMNIGIFLKQFKK--SPQSIVEDIHQGRSEHYGSETLREILKLLPESEEVKKLKTFNG 230

  Fly   750 KGEPLPPIEQFAATIGEIKRLSPRLHNLNFKLTYADMVQDIKPDIVAGTAACEEIRNSKKFSKIL 814
            ....|...:.|...:.::...|.|:..:..|..:......:..||....||.:|:...::...||
  Rat   231 DVSKLSLADSFLYCLIQVPNYSLRIEAMVLKKEFLPFCTSLYKDITTLRAAMKELMLCEELHSIL 295

  Fly   815 ELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTLLHYLADLVEKKFPDALNFYDDLS 879
            .|:|..||.||:|.....|.||::|.|.||::||.......|||::|...:|.....|||.:.|.
  Rat   296 HLVLQAGNIMNAGGYAGNAVGFKLSSLLKLADTKANKPGMNLLHFVAQEAQKHNTILLNFSEKLQ 360

  Fly   880 HVNKASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQCDDDKFSEVMGKFAEECRQQVDVLGKM 944
            .|.:.||:::|.|:..:..:....|:|..::|.::..:...:.|.:    ||.|...::: |.|.
  Rat   361 QVQETSRLSLDIIEAELHSLFVRTKSLRENIQRDQELRQQMEDFLQ----FAVEKLAELE-LWKR 420

  Fly   945 QLQMEKLYKDLSEYYAFDPSKYTMEEFFADIKTFKDAFQAAHNDNVRVREELEKK--RRLQEARE 1007
            :||:|.  ..|.:::..|.....::|.|...:.|...|..|..|| ..|||.|:|  :||:|..:
  Rat   421 ELQVEA--HTLIDFFCEDKETMKLDECFQIFRDFCTRFNKAVKDN-HDREEQERKQLQRLKELEQ 482

  Fly  1008 --------------QSAREQQERQQRKKAVVDMDA-------------PQTQEGVMD-------S 1038
                          :|:.|...:...||...|:.:             |.|:...:.       .
  Rat   483 KRHSWTTGELGGFGRSSSENDVQMLAKKGTEDLPSFLKPRPNSPSYRPPNTRRSRLSLGISADRE 547

  Fly  1039 LLEALQTGSA-------FGQRNRQARRQRPAGAERRAQLSRSRSRTRVTNGQLMTRE 1088
            ||..|::.::       |....|.:.||      .|..::....|.:.|:|.:.|.:
  Rat   548 LLTFLESATSSPEDPNKFNSLPRSSPRQ------TRPTIAWMEPREQETHGPVFTHD 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dia	NP_001246113.1	Drf_GBD	66..248	CDD:283920
		Drf_FH3	253..453	CDD:283917
		FH2	608..983	CDD:280362	90/388 (23%)
Fhdc1	NP_001099907.1	FH2	93..457	CDD:396655	90/387 (23%)
		PTZ00449	<559..760	CDD:185628	9/46 (20%)
		PHA03307	733..>1128	CDD:223039

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920