DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dia and LOC101882656

DIOPT Version :9

Sequence 1:	NP_001246113.1	Gene:	dia / 35340	FlyBaseID:	FBgn0011202	Length:	1098	Species:	Drosophila melanogaster
Sequence 2:	XP_005174706.2	Gene:	LOC101882656 / 101882656	-ID:	-	Length:	315	Species:	Danio rerio

Alignment Length:	343	Identity:	79/343 - (23%)
Similarity:	153/343 - (44%)	Gaps:	60/343 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   638 VKCQEDKLAQDDFLAELAVKFSSKPVKKEQKDAVDKP--TTLTKKNVDLRVLDSKTAQNLAIMLG 700
            |.||::|...:               |..:...:.||  .:|.:|:: :::||.|.:|.:.|::
Zfish     4 VPCQDEKRNYE---------------KNYEFKGMFKPPGLSLVRKSI-IKLLDGKRSQAVGILI- 51

  Fly   701 GSLKHLSYEQIKICLLRCDTDILSSNILQQLIQYLPPPEHLKRLQ---------EIKAKGEPLPP 756
             |..||..:.|:..:|..|..::....::.|.:....|:.|::::         |:|...:|
Zfish    52 -SSLHLEMKDIQQAVLTVDHSVVDLETIEALYENRAQPDELEKIKKHYESSKEDELKLLDKP--- 112

  Fly   757 IEQFAATIGEIKRLSPRLHNLNFKLTYADMVQDI--KPDIVAGTAACEEIRNSKKFSKILELILL 819
             |||...:.:|...:.|.|.:.|:..:.|.:..:  |.:|:  :..|:...::.....::.:||.
Zfish   113 -EQFLYELSQIPDFAGRSHCIIFQSVFVDSISSVCRKVEII--STVCKVFLDNDSVKDVIGVILA 174

  Fly   820 LGNYMNSGSKNEA-AFGFEISYLTKLSNTKDADNKQTLL-----HYLADLVEKKFPDALNF---- 874
            .|||||.|::... |.||.:..|.||.:.|..||:.:|:     :||.::.|....|...|
Zfish   175 FGNYMNGGNRTRGQADGFGLEILPKLKDVKSRDNRMSLVDYVVSYYLRNMDENAGTDKSVFPLPE 239

  Fly   875 YDDLSHVNKASRVNMDAIQKAMR----QMNSAVKNLETDLQNNKVPQCDD--DKFSEVMGKFAEE 933
            ..||.|   |::|..:.:.|.:|    ::.:.||.:|...:|:.    |:  ..|.:.|..|...
Zfish   240 PQDLFH---AAQVKFEDLAKDLRKLKKELTACVKEVEQVCENSS----DEHLQPFKDKMETFIST 297

  Fly   934 CRQQVDVLGKMQLQMEKL 951
            ...|.....||:.:.:.|
Zfish   298 GESQKGCYLKMKCERDML 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dia	NP_001246113.1	Drf_GBD	66..248	CDD:283920
		Drf_FH3	253..453	CDD:283917
		FH2	608..983	CDD:280362	79/343 (23%)
LOC101882656	XP_005174706.2	FH2	32..301	CDD:302999	67/284 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010