Protein Alignment dia and fhdc1

DIOPT Version :9

• Sequence 1: NP_001246113.1
• Gene: dia / 35340
• FlyBaseID: FBgn0011202
• Length: 1098
• Species: Drosophila melanogaster
• Sequence 2: XP_001920056.2
• Gene: fhdc1 / 100148864
• ZFINID: ZDB-GENE-040826-4
• Length: 1165
• Species: Danio rerio
• Alignment Length: 606
• Identity: 145/606 - (23%)
• Similarity: 244/606 - (40%)
• Gaps: 128/606 - (21%)

  Fly   502 ANGVAAPSPNKLPKVNIPMPPPPPGGGGAPPPPPPPMPGRAGGGPPPPPPPPMPGRAGGPPPPPP 566
            ||....|..|.||..:..........|......||.:        |||||||       |||||.
Zfish    14 ANESTTPIGNPLPLKSSTTSTNDQSQGRDSNTCPPAV--------PPPPPPP-------PPPPPQ 63

  Fly   567 PPGMGGPPPPPMPGMMRPGGGPPPPPMMMGPMVPVLPHGLKPKKKWDVKNPMKRANWKAIVPAKM 631
            .||..|                              .|..:.|::      ::...||.|...|:
Zfish    64 APGNSG------------------------------QHASRKKRR------VRSFFWKTIPEEKV 92

  Fly   632 SDKA-FW------------VKCQEDKLAQDDFLAELAVKFS--------SKPVKKEQKDAVDKPT 675
            ..|. .|            ||..|:...|.:   |:..:.|        |:...||.||
Zfish    93 RGKPNIWTLAVRQQQYQIDVKTVEELFGQQE---EVRTQTSGGHSRTGRSRGSFKESKD------ 148

  Fly   676 TLTKKNVDLRVLDSKTAQNLAIMLGGSLK--HLSYEQIKICLLRCDTDILSSNILQQLIQYLPPP 738
                   ::.:||||...|:.|.|....|  |...|.|::    .::....:..|::|::.||..
Zfish   149 -------EISILDSKRGMNIGIFLKQFKKSNHAIVEDIRL----FNSKQYGAEPLKELLKLLPEA 202

  Fly   739 EHLKRLQEIKAKGEPLPPIEQFAATIGEIKRLSPRLHNLNFKLTYADMVQDIKPDIVAGTAACEE 803
            :.:|||:|.|.....|..::.|...:.::.|...|:..:..:..:..:...:..||.....|.|:
Zfish   203 DEVKRLREFKGDANKLTLVDSFMFQLIQVPRFDVRIEVMVLQEEFFPLCTAMSRDINIVRQATED 267

  Fly   804 IRNSKKFSKILELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTLLHYLADLVEKKF 868
            :.|.::...||.|:|..||.||:|.....|.||::|.|..|::||.......|||::|...:||.
Zfish   268 LMNCEELHAILHLVLQAGNIMNAGGYAGNAVGFKLSSLLSLADTKANKPGMNLLHFVALEAQKKD 332

  Fly   869 PDALNFYDDLSHVNKASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQCDDDKFSEVMGKFAEE 933
            ...|.|.:.|:|:..|:|::::.|:.....:....::||..:|       |||:..:.:..|.:.
Zfish   333 EALLKFPEKLTHIQSAARISVENIEGEFSSLYVKTRSLEQKIQ-------DDDELQKQLDPFLQS 390

  Fly   934 CRQQVDVLGKMQLQMEKLYKDLSEYYAFDPSKYTMEEFFADIKTFKDAFQAAHNDNVRVREELEK 998
            ..:.:..|...:|.:.|....|.:::..|...:.::|.|...:.|...|:.|..||    .:.|.
Zfish   391 SAKALQDLKHRRLDLRKEGNALIDFFCEDKDTFKLDECFRIFQDFCLKFKKAVKDN----SDREL 451

  Fly   999 KRRLQEAREQSAREQQERQ----------------QRKKAVVDMDAPQTQEGVMDSLLEALQTG- 1046
            |   :|||::..||.:||:                .|..:..|:|. .|::|::|.||::....
Zfish   452 K---EEARQRRLRELEERRCAWGAANIETGGNGGFGRSSSENDVDI-LTKDGLLDFLLQSRPQSP 512

  Fly  1047 -SAFGQRNRQARRQRPAGAER 1066
             |..| |:..|||.....::|
Zfish   513 HSPLG-RSASARRYHHTSSDR 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dia	NP_001246113.1	Drf_GBD	66..248	CDD:283920
		Drf_FH3	253..453	CDD:283917
		FH2	608..983	CDD:280362	92/397 (23%)
fhdc1	XP_001920056.2	FH2	74..440	CDD:280362	92/398 (23%)
		Herpes_ICP4_C	922..>1134	CDD:332854

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920