Protein Alignment Rhau and PRP2

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_014408.1
• Gene: PRP2 / 855745
• SGDID: S000005294
• Length: 876
• Species: Saccharomyces cerevisiae
• Alignment Length: 929
• Identity: 254/929 - (27%)
• Similarity: 423/929 - (45%)
• Gaps: 204/929 - (21%)

  Fly    10 SNARKGNRPPGLRGKDIGLYYRNLARQQKKDRGENAESKEPQIRLGCNVSAPSGVLERVKELMED 74
            ||..:|.....|:|:.:|        .|||     :...:.:|.....::...|:|.. .|....
Yeast    63 SNTNQGPEKNNLKGEQLG--------SQKK-----SSKYDEKITSNNELTTKKGLLGD-SENETK 113

  Fly    75 YSRAPSRQNVD-------DKNVDAKF-------QQQFRHLLS--------VNFE-----EFVAET 112
            |:.:.|:.||:       .|.:| |.       :||.|:.::        :..|     ::|.:|
Yeast   114 YASSNSKFNVEVTHKIKNAKEID-KINRQRMWEEQQLRNAMAGQSDHPDDITLEGSDKYDYVFDT 177

  Fly   113 KERNADLDWVNPKLD----ERLQLELGQRQLEENAKKRL----EARKKLPTMKYADDIIQAVREN 169
               :|.:|:.|.:.|    |:||.|....|..|..:||:    ||||.||..:|.|:::|.:::|
Yeast   178 ---DAMIDYTNEEDDLLPEEKLQYEARLAQALETEEKRILTIQEARKLLPVHQYKDELLQEIKKN 239

  Fly   170 QVILIVGSTGCGKTTQVPQILLDDAISRGCASSCRIICTQPRRISAIAIAEWVSYERCESLGNSV 234
            ||::|:|.||.|||||:||.|::|..:.  ....:|..|||||::|.::|..|:.|....||..|
Yeast   240 QVLIIMGETGSGKTTQLPQYLVEDGFTD--QGKLQIAITQPRRVAATSVAARVADEMNVVLGKEV 302

  Fly   235 GYQIRLESRKARERASITYCTTGVLLQQLQSDPLMHNLSVLILDEIHERSVETDLLMGLLKVILP 299
            |||||.|.:....:..:.|.|.|:||::..:|..:...|.:::||.|||::.||:|:||||.|||
Yeast   303 GYQIRFEDKTTPNKTVLKYMTDGMLLREFLTDSKLSKYSCIMIDEAHERTLATDILIGLLKDILP 367

  Fly   300 HRPDLKVILMSATVREQDFCDYFNNCPMFRIEGVMFPVKMLYLEDVLSKTNYEFQKFRDRRPKRD 364
            .||.||:::.|||:..:.|.::|:|||:|.:.|..:||.:          :|..|
Yeast   368 QRPTLKLLISSATMNAKKFSEFFDNCPIFNVPGRRYPVDI----------HYTLQ---------- 412

  Fly   365 PPERRMKHEAMIEPYLRRIRNSYDSRVLDKLRLPESEGCEDIDFIADLVYYICENEPEGAILVFL 429
             ||....|.|:...:......|          ||                        |.|||||
Yeast   413 -PEANYIHAAITTIFQIHTTQS----------LP------------------------GDILVFL 442

  Fly   430 PGYDKISQLYNILDKPKTSKGQRWRDHMAVFPLHSLMQSGEQQAVFRRPPAGQRKVIISTIIAET 494
            .|.::|.:....|::..:..|.|.: .|.:.|:::.:...:|..:|:..|...|||:::|.||||
Yeast   443 TGQEEIERTKTKLEEIMSKLGSRTK-QMIITPIYANLPQEQQLKIFQPTPENCRKVVLATNIAET 506

  Fly   495 SVTIDDVVYVINSGRTKATNYDIETNIQSLDEVWVTKANTQQRRGRAGRVRPGICYNLFSR-ARE 558
            |:|||.:.|||:.|..|..:|...|.:..|..|..::|:..||.||||||.||.|:.:|:: :..
Yeast   507 SLTIDGIRYVIDPGFVKENSYVPSTGMTQLLTVPCSRASVDQRAGRAGRVGPGKCFRIFTKWSYL 571

  Fly   559 DRMDDIPTPEILRSKLESIILSLKLLHIDDPYRFLQTLINAPNPEAIKMGVELLKRIEALDQTGT 623
            ..::.:|.|||.|:.|.:.:|.|..|.:.|..:|  .|::.|:...::..:|.|..:.||:..||
Yeast   572 HELELMPKPEITRTNLSNTVLLLLSLGVTDLIKF--PLMDKPSIPTLRKSLENLYILGALNSKGT 634

  Fly   624 LTPLGMHLAKLPIDPQMGKMILMSALF--C------CLDPIT---------------SAAAALSF 665
            :|.||..:.:.|.:|:..|::..:|..  |      ||..::               :||:.||
Yeast   635 ITRLGKMMCEFPCEPEFAKVLYTAATHEQCQGVLEECLTIVSMLHETPSLFIGQKRDAAASVLS- 698

  Fly   666 KSPFYSPLGKESRVDEIKRRMARNMRSDHLMVHNTIIAYRDSRYSHAERDFCYKNFLSSMTLQQL 730
                                   .:.|||::.......:|:|::|   |.:|..:.:...|:.::
Yeast   699 -----------------------EVESDHILYLEIFNQWRNSKFS---RSWCQDHKIQFKTMLRV 737

  Fly   731 ERMKNQFSELLYNYKFLASSNCKDAASNKNSE---KIPLLRAIIGA--------GLYPNMAHLRK 784
            ..::||.        |..|.  |.....||.:   ||..:...|.|        |...|:..|..
Yeast   738 RNIRNQL--------FRCSE--KVGLVEKNDQARMKIGNIAGYINARITRCFISGFPMNIVQLGP 792

  Fly   785 SRQIKNRVRAIHTMA-TDDGRRVNFHPSS---VNSGESGFDSAYFVYFQRQKSTDLFLLDSTMVF 845
            :        ...||. :..|..|:.||:|   ||..|.....:.:|.:|:...|....:...:|.
Yeast   793 T--------GYQTMGRSSGGLNVSVHPTSILFVNHKEKAQRPSKYVLYQQLMLTSKEFIRDCLVI 849

  Fly   846 P-------MALIIFGDGVE 857
            |       |...||.|.::
Yeast   850 PKEEWLIDMVPQIFKDLID 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	165/527 (31%)
		OB_NTP_bind	767..856	CDD:400182	24/107 (22%)
PRP2	NP_014408.1	PTZ00121	<7..174	CDD:173412	24/125 (19%)
		HrpA	223..>738	CDD:441249	179/601 (30%)
		OB_NTP_bind	775..862	CDD:400182	19/94 (20%)