Protein Alignment Rhau and DHR2

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_012845.1
• Gene: DHR2 / 853784
• SGDID: S000001561
• Length: 735
• Species: Saccharomyces cerevisiae
• Alignment Length: 772
• Identity: 220/772 - (28%)
• Similarity: 355/772 - (45%)
• Gaps: 128/772 - (16%)

  Fly    78 APSRQNVDDKNVDAKFQQQFRHLLSVNFEEFVAETKERNA----------DLDWVNPKLDERLQL 132
            |.|...|...:...|  |:.|.    |...|...|:.:.|          :.|.|:   |:|...
Yeast     3 ANSNSRVASNHTSKK--QKVRR----NIHPFTNNTRIKRASKIVKFNDSGEGDHVS---DQRSNK 58

  Fly   133 E--LGQRQLEENAKKRLEARKKLPTMKYADDIIQAVRENQVILIVGSTGCGKTTQVPQILLD--- 192
            |  |..:.|:..|...|:.|:.||..::..:|:..:..|.|.:::|.||.||:||:||.:|:
Yeast    59 ENVLTYKSLKSRASDLLKMRETLPVYQHKREIMSYIESNPVTVLIGETGSGKSTQIPQFVLEKLY 123

  Fly   193 DAISRGCASSCRIICTQPRRISAIAIAEWVSYERCESLGNSVGYQIRLESRKARERASITYCTTG 257
            |....|     .|..|||||::||.:|..|:.|....||..|||.:|.:: ....|..:.|.|.|
Yeast   124 DTKKHG-----SIAVTQPRRVAAINLATRVAQEHGCKLGEQVGYSVRFDN-TTTTRTRLKYLTDG 182

  Fly   258 VLLQQLQSDPLMHNLSVLILDEIHERSVETDLLMGLLK-VILPHRPDLKVILMSATVREQDFCDY 321
            :||::|..:..:...||:::||.|||:|.|||::|.|| :|...||||::|:||||::.:.|.::
Yeast   183 MLLRELMMNSDLREYSVIVIDEAHERTVLTDLILGFLKSLIQGPRPDLRIIVMSATLQAEKFSEF 247

  Fly   322 FNNCPMFRIEGVMFPVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNS 386
            |||.|:..:||..|.||..||                :.|..|
Yeast   248 FNNAPILFVEGRKFDVKQYYL----------------KAPTDD---------------------- 274

  Fly   387 YDSRVLDKLRLPESEGCEDIDFIADLVYYIC----ENEPEGAILVFLPGYDKISQLYNILDK-PK 446
                                  |.|.|...|    :.|..|.||.||||.::|.:...|::| .|
Yeast   275 ----------------------IVDAVIRCCIQINQGEELGDILCFLPGQEEIDKAVTIMEKIAK 317

  Fly   447 TSKGQRWRDHMAVFPLHSLMQSGEQQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTK 511
            ....:.....:..:||::.:.:.:|..||......:|||:.||.||||||||..|.:|::||..|
Yeast   318 YVSDEAPVPLIVPYPLYAALPAVQQSLVFAPIKGFKRKVVFSTNIAETSVTISGVKFVVDSGLRK 382

  Fly   512 ATNYDIETNIQSLDEVWVTKANTQQRRGRAGRVRPGICYNLFSRAREDRMDDIPTPEILRSKLES 576
            ...:..:..:.:|..|.:::|:..||.|||||...|..:.|:..:...::.....|||.||.:.|
Yeast   383 VKVWRHQLGLATLLTVPISQASAMQRSGRAGRESEGKSFRLYCESDYVKLPKQSEPEIARSDVTS 447

  Fly   577 IILSLKLLHIDDPYRFLQTLINAPNPEAIKMGVELLKRIEALDQTGTLTPLGMHLAKLPIDPQMG 641
            .:|.||...:||...:  |....|..|||.||::.|..:.|||..|.:|..|..:|.||:.|.:.
Yeast   448 PVLMLKRYGVDDLLNW--TWFENPGKEAIVMGLQELYELGALDTRGKITKRGQQMALLPLQPHLS 510

  Fly   642 KMILMSALFCCLDPITSAAAALSFKSPFYSPLGKESRVDEIKRRM-----ARNMRSDHLMVHNTI 701
            .:::.::...||..:....:.||.::...:|..:|.  ||:..|.     |.....|.:|:....
Yeast   511 SVLIKASEVGCLSQVIDIVSCLSVENLLLNPSPEER--DEVNERRLSLCNAGKRYGDLIMLKELF 573

  Fly   702 IAY----RDSRYSHAER-DFCYKNFLSSMTLQQLERMKNQFSELLYNYKFLASSNCKDAASNKNS 761
            ..|    ..|:.:.:|| |:|....:|....:.:.|:::|..  :|..:..:|.:.:|..|.|..
Yeast   574 DIYFYELGKSQDASSERNDWCKGLCISIRGFKNVIRVRDQLR--VYCKRLFSSISEEDEESKKIG 636

  Fly   762 EKIPLLRAIIGAGLYPNMAHLRKSRQIKNRV-----RAIHTMATDDGRRVNFHPSSV 813
            |...|:..|:...|         :..|||..     |:..|::|  |..::.||||:
Yeast   637 EDGELISKILKCFL---------TGFIKNTAIGMPDRSYRTVST--GEPISIHPSSM 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	159/512 (31%)
		OB_NTP_bind	767..856	CDD:400182	13/52 (25%)
DHR2	NP_012845.1	HrpA	79..>534	CDD:441249	162/522 (31%)
		OB_NTP_bind	645..722	CDD:400182	13/49 (27%)