Protein Alignment Rhau and PRP43

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_011395.1
• Gene: PRP43 / 852757
• SGDID: S000003088
• Length: 767
• Species: Saccharomyces cerevisiae
• Alignment Length: 848
• Identity: 251/848 - (29%)
• Similarity: 398/848 - (46%)
• Gaps: 131/848 - (15%)

  Fly    62 SGVLERVKELMEDYSR---APSRQNVDDKNVDAKFQQQFRHLLSVNFEEFVAETKERNADLDWVN 123
            :.:.|:..|:.|:.|:   .||.:.:...:. .:|:...||..|....:.:.:.|        :|
Yeast    17 TSIPEQAAEIAEELSKQHPLPSEEPLVHHDA-GEFKGLQRHHTSAEEAQKLEDGK--------IN 72

  Fly   124 PKLDERLQLELGQRQLEENAKKRLEARKKLPTMKYADDIIQAVRENQVILIVGSTGCGKTTQVPQ 188
            |         ...|:........|:.|::||.....|:.::..:.||:::.||.||.|||||:||
Yeast    73 P---------FTGREFTPKYVDILKIRRELPVHAQRDEFLKLYQNNQIMVFVGETGSGKTTQIPQ 128

  Fly   189 ILLDDAISRGCASSCRIICTQPRRISAIAIAEWVSYERCESLGNSVGYQIRLESRKARERASITY 253
            .:|.|.:..  ..:.::.||||||::|:::|:.|:.|....||..|||.||.|: |...:..:.|
Yeast   129 FVLFDEMPH--LENTQVACTQPRRVAAMSVAQRVAEEMDVKLGEEVGYSIRFEN-KTSNKTILKY 190

  Fly   254 CTTGVLLQQLQSDPLMHNLSVLILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSATVREQDF 318
            .|.|:||::...|..:...|.:||||.|||::.||:||||||.::..|||||:|:||||:..:.|
Yeast   191 MTDGMLLREAMEDHDLSRYSCIILDEAHERTLATDILMGLLKQVVKRRPDLKIIIMSATLDAEKF 255

  Fly   319 CDYFNNCPMFRIEGVMFPVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRI 383
            ..|||:.|:..:.|..:||::.|..        |||
Yeast   256 QRYFNDAPLLAVPGRTYPVELYYTP--------EFQ----------------------------- 283

  Fly   384 RNSYDSRVLDKLRLPESEGCEDIDFIADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPKTS 448
            |:..||.:...|:                   |...|..|.||:||.|.|:|.   :.:.|....
Yeast   284 RDYLDSAIRTVLQ-------------------IHATEEAGDILLFLTGEDEIE---DAVRKISLE 326

  Fly   449 KGQRWRDH----MAVFPLHSLMQSGEQQAVFRRPPAGQ-----RKVIISTIIAETSVTIDDVVYV 504
            ..|..|:.    ::|:||:..:...:||.:|...|...     |||:|||.|||||:|||.:|||
Yeast   327 GDQLVREEGCGPLSVYPLYGSLPPHQQQRIFEPAPESHNGRPGRKVVISTNIAETSLTIDGIVYV 391

  Fly   505 INSGRTKATNYDIETNIQSLDEVWVTKANTQQRRGRAGRVRPGICYNLFS-RAREDRMDDIPTPE 568
            ::.|.:|...|:....::||....::||:.|||.|||||.|||.|:.|:: .|.:..:.:...||
Yeast   392 VDPGFSKQKVYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFQKELIEQSYPE 456

  Fly   569 ILRSKLESIILSLKLLHIDDPYRFLQTLINAPNPEAIKMGVELLKRIEALDQTGTLTPLGMHLAK 633
            ||||.|.|.:|.||.|.|||...|  ..::.|.||.:...:|.|..:..||..|.|||||...::
Yeast   457 ILRSNLSSTVLELKKLGIDDLVHF--DFMDPPAPETMMRALEELNYLACLDDEGNLTPLGRLASQ 519

  Fly   634 LPIDPQMGKMILMSALFCCLDPITSAAAALSFKSPFYSPLGKESRVDEIKRRMARNMRSDHLMVH 698
            .|:||.:..|::.|..|.|...|.:..|.||..:.|..|...:.|.|:.|...| :...||:.:.
Yeast   520 FPLDPMLAVMLIGSFEFQCSQEILTIVAMLSVPNVFIRPTKDKKRADDAKNIFA-HPDGDHITLL 583

  Fly   699 NTIIAYR-DSRYSHAERDFCYKNFLSSMTLQQLERMKNQFSELLYNYKFLASSNCKDAASNKNSE 762
            |...|:: |..|.:....:|..::|:..:|...:.:::|...|:..|..  ..|..|..|.|..:
Yeast   584 NVYHAFKSDEAYEYGIHKWCRDHYLNYRSLSAADNIRSQLERLMNRYNL--ELNTTDYESPKYFD 646

  Fly   763 KIPLLRAIIGAGLYPNMAHLRKSRQIKNRVRAIHTMATDDGRRVNFHPSSVNSGESGFDSAYFVY 827
            .|   |..:.:|.:..:|        |.|..|...:...|.:.|..|||:|    .|.|:.:.:|
Yeast   647 NI---RKALASGFFMQVA--------KKRSGAKGYITVKDNQDVLIHPSTV----LGHDAEWVIY 696

  Fly   828 FQRQKSTDLFLLDSTMVFPMALIIFGDGVEAGVTQNTPYLCVAKTYYFKCNRETADVVIQLRSNL 892
            .:...::..::...|.|.|..||.                 :|..||...|.:..||.:.|....
Yeast   697 NEFVLTSKNYIRTVTSVRPEWLIE-----------------IAPAYYDLSNFQKGDVKLSLERIK 744

  Fly   893 EKL 895
            ||:
Yeast   745 EKV 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	179/513 (35%)
		OB_NTP_bind	767..856	CDD:400182	20/88 (23%)
PRP43	NP_011395.1	FlhF	<12..>124	CDD:274609	27/124 (22%)
		HrpA	92..>724	CDD:441249	227/730 (31%)