Protein Alignment Rhau and Dhx30

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001239612.1
• Gene: Dhx30 / 72831
• MGIID: 1920081
• Length: 1223
• Species: Mus musculus
• Alignment Length: 960
• Identity: 303/960 - (31%)
• Similarity: 495/960 - (51%)
• Gaps: 130/960 - (13%)

  Fly    24 KDIGLYYR----------NLARQQKKDRGENAESKEPQIRLGCNVSAPSGVLERVKELMEDYSRA 78
            |.:||..|          |||  ..::.||..       |..|.:..|..:|.:::..:..|.
Mouse   342 KSLGLVDRNNEPLTHAMYNLA--SLRELGETQ-------RRPCTIQVPEPILRKIEAFLSHYP-- 395

  Fly    79 PSRQNVDDKNVDAKFQQQFRHLLSVNFEEFVAETKERNADLDWVNPK----LDERLQLELGQRQL 139
                 ||...:..:.:.|...:|.:.        |:.....|.:..|    |.|..::.|.|..|
Mouse   396 -----VDSSWISPELRLQSDDILPLG--------KDSGPLSDPITGKPYMPLSEAEEVRLSQSLL 447

  Fly   140 EENAKKRLEARK--------KLPTMKYADDIIQAVRENQVILIVGSTGCGKTTQVPQILLDDAIS 196
            |      |..|:        :||...:.|.|:.|:.::.|::|.|.|||||||::||:||:..::
Mouse   448 E------LWRRRGPIWQEAPQLPVDPHRDTILSAIEQHPVVVISGDTGCGKTTRIPQLLLERYVT 506

  Fly   197 RGCASSCRIICTQPRRISAIAIAEWVSYERCESLGNSVGYQIRLESRKARERASITYCTTGVLLQ 261
            .|..:.|.:|.||||||||:::|:.||:|...||..:||:|:||||:......::.:||.|:||:
Mouse   507 EGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLR 571

  Fly   262 QLQSDPLMHNLSVLILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSATVREQDFCDYFNNCP 326
            :|||:|.:..:|.:|:||:|||.|.||.|:.|||.:....|.|:::|||||...:.|..||..||
Mouse   572 KLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCP 636

  Fly   327 MFRIEGVMFPVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNSYDSRV 391
            :.::.|.|:|||..||||:|:|..           |...|.|...||:
Mouse   637 VIKVPGFMYPVKEHYLEDILAKLG-----------KHQYPHRHRHHES----------------- 673

  Fly   392 LDKLRLPESEGCEDIDFIADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPKTSKGQRWRDH 456
                   |.|...|:|.:.|||.:|......|.||.||||:.:|.   .:..:.:.:.|.....:
Mouse   674 -------EDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIK---GVQQRLQEALGMHESKY 728

  Fly   457 MAVFPLHSLMQSGEQQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNI 521
            : :.|:||.:...:|:|:|::||.|.||::::|.|||||:|::|:|:|::||..|...||::|.:
Mouse   729 L-ILPVHSNIPMMDQKAIFQQPPLGVRKIVLATNIAETSITVNDIVHVVDSGLHKEERYDLKTKV 792

  Fly   522 QSLDEVWVTKANTQQRRGRAGRVRPGICYNLFSRAREDRMDDIPTPEILRSKLESIILSLKLLHI 586
            ..|:.|||::||..||||||||.:.|..|:||.|:|.::|.....|||||:.||:::|..| :|:
Mouse   793 SCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAK-IHM 856

  Fly   587 DD--PYRFLQTLINAPNPEAIKMGVELLKRIEALDQTGTLTPLGMHLAKLPIDPQMGKMILMSAL 649
            .:  ...||...:::||.:|:...|.||:.|..|||...||.||..||.:..||::.|.|:::|:
Mouse   857 PEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAI 921

  Fly   650 FCCLDPITSAAAALSFKSPFYSPLGKESRVDEIKRRMARNMRSDHLMVHNTIIAY--------RD 706
            |.||.|:....:.|: :.||.|.|...:.||::|..::.:..||||.....:..:        |.
Mouse   922 FRCLHPLLVVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRT 985

  Fly   707 SRYSHAERDFCYKNFLSSMTLQQLERMKNQFSELLYNYKFLAS--SNC--KDAASNKNSEKIPLL 767
            ||.::.|     :|.|.:.:|:.:..:..||||.:|. .||..  |:|  ..|..|:.||:..|:
Mouse   986 SRENYLE-----ENLLYAPSLRFIHGLIKQFSENIYE-AFLVGKPSDCTLPSAQCNEYSEEEELV 1044

  Fly   768 RAIIGAGLYPNMAHLRK---SRQIKNRVRAIHTMATDDGRRVNFHPSSVNSGESGFDSAYFVYFQ 829
            :.::.||||||:..:|:   :||.|.:..:: |..|..| .:..|.|::|...:...|.:..||.
Mouse  1045 KGVLMAGLYPNLIQVRQGKVTRQGKFKPNSV-TYRTKSG-NILLHKSTINREATRLRSRWLTYFM 1107

  Fly   830 RQKST-DLFLLDSTMVFPMALIIFGDG---VEAGVTQNTPYLCVAKTYYFKCNRETADVVIQLRS 890
            ..||. .:|:.||:.|.|:|:::..||   :.....:.|..|..:.....:.:..|..::.:.|.
Mouse  1108 AVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLREFRR 1172

  Fly   891 NLEKLL---LKKALYPAPIEENGYEKQLIKAIELLL-----SLDERLGED 932
            .|.:::   |:..|...|:.......||:..:..||     |.|.|...|
Mouse  1173 ALGRMVERSLRSELAALPLSVQQEHGQLLALLAELLRGPCGSFDMRKTAD 1222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	194/505 (38%)
		OB_NTP_bind	767..856	CDD:400182	29/95 (31%)
Dhx30	NP_001239612.1	HrpA	455..>987	CDD:441249	209/572 (37%)
		OB_NTP_bind	1044..1131	CDD:400182	27/88 (31%)