Protein Alignment Rhau and Dhx34

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_082159.3
• Gene: Dhx34 / 71723
• MGIID: 1918973
• Length: 1145
• Species: Mus musculus
• Alignment Length: 1115
• Identity: 307/1115 - (27%)
• Similarity: 472/1115 - (42%)
• Gaps: 314/1115 - (28%)

  Fly     3 RDRDSSGSNARKGNRPPGLRGKDIGLYYRNLARQQKKDRGENAESKE----PQIRLGCNVSAPSG 63
            |.|:..|...|..:|.|                     |.|.|..|.    |:.|  |
Mouse     5 RTREGRGHRDRDHHRAP---------------------REEEAPEKWDWNCPETR--C------- 39

  Fly    64 VLERVKELMEDYSRAPSRQNVDDKNVDAKFQ--QQFRHLLS------------------------ 102
            :||.|....|||.|   |.:.:.:...|.|:  |:|:||.:
Mouse    40 LLEDVFFRDEDYIR---RGSEECQKFWAFFERLQRFQHLKTSQKKEKDPGMPKHGIAALADLPLT 101

  Fly   103 ------VNFEEFVAETKERNADLDWVNPKLDERLQ---------LELGQRQLEENAKKRLEARKK 152
                  :|......:|:.|:.....:.|   ||:.         |:..|:|......|....|..
Mouse   102 YDPRYRINLSILSPDTRGRHGPGRGLPP---ERVSEFRRALLHYLDFQQKQAFGRLVKLQRERAA 163

  Fly   153 LPTMKYADDIIQAVRENQVILIVGSTGCGKTTQVPQILLDDAISRGCASSCRIICTQPRRISAIA 217
            ||..:|.:.|:|.::|:||:::.|.|||||:|||||.||       .|....:.|||||||:.|:
Mouse   164 LPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLL-------AAGFSHVACTQPRRIACIS 221

  Fly   218 IAEWVSYERCESLGNSVGYQIRLESRKARERASITYCTTGVLLQQLQSDPLMHNLSVLILDEIHE 282
            :|:.|.:|.....|:.||||||.||.:: ....|.:.|.|:||:|:|.:|.:....|||:||:||
Mouse   222 LAKRVGFESLSQYGSQVGYQIRFESTRS-AATKIVFLTVGLLLRQIQREPSLPQYQVLIVDEVHE 285

  Fly   283 RSVETDLLMGLLKVILPHRPDLKVILMSATVREQDFCDYFNNCPMFRIEGVMFPVKMLYLEDVLS 347
            |.:..|.|:|:|:.:||.||||||||||||:....|..||::.|:.::.|.:||:.::|......
Mouse   286 RHLHNDFLLGVLQRLLPQRPDLKVILMSATINISLFSSYFSHAPVVQVPGRLFPITVVYQPQEAD 350

  Fly   348 KTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLR---RIRNSYDSRVLDKLRLPESEGCEDIDFI 409
            :|       ..:..|.||           .|:||   .|.|.|..
Mouse   351 QT-------ASKSEKLDP-----------RPFLRVLEAIDNKYPP-------------------- 377

  Fly   410 ADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPK--TSKGQRWRDHMAVFPLHSLMQSGEQQ 472
                      |..|.:||||.|   ::::..:||..:  .|..|||    .|.||||.:...:|.
Mouse   378 ----------EERGDLLVFLSG---MAEITTVLDAAQAYASLTQRW----VVLPLHSALSVSDQD 425

  Fly   473 AVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNIQSLDEVWVTKANTQQR 537
            .||...|||.||.|:||.|||||||||.:.:|::||:.|..:||.:..:|.|.|.|:::|:.:||
Mouse   426 KVFDVAPAGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQR 490

  Fly   538 RGRAGRVRPGICYNLFSRAREDRMDDIPTPEILRSKLESIILSLKLLHIDDPYRFLQTLINAPNP 602
            :|||||..||:||.|::.:..|.....|.|||.|..|::::|.:|.:.:.||..|  ..|..|.|
Mouse   491 KGRAGRTGPGVCYRLYAESDYDAFAPYPVPEIRRVALDALVLQMKSMSVGDPRTF--PFIEPPPP 553

  Fly   603 EAIKMGVELLKRIEALDQTGTLTPLGMHLAKLPIDPQMGKMILMSALFCCLDPITSAAAALSFKS 667
            .:::..:..|:...|||.:..|||:|..||:||:|..:|||:::.::|...:|:.:.|||||.:|
Mouse   554 ASVETAILYLQEQGALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLAEPVLTIAAALSVQS 618

  Fly   668 PFYSPLGKESRVD-EIKRRMARNMRSDHLMVHNTIIAYRD--SRYSHAERDFCYKNFLSSMTLQQ 729
            ||  ....:|.:| ...||...:.:.|...:.|...|:..  |..|...|.:|.:..:....|.:
Mouse   619 PF--TRSAQSNLDCATARRPLESDQGDPFTLFNVFNAWVQVKSERSGNSRKWCRRRGVEEHRLYE 681

  Fly   730 LERMKNQFSELLYNYKFLA---------------------------------------------- 748
            :..::.||.|||.::..|:
Mouse   682 MANLRRQFKELLEDHGLLSGAQVVAPGDSYSRLQQRRERRALHQLKRQHEEGGGRRRKVLRLQED 746

  Fly   749 --SSNCKD---------------------------------AASNKNSEKIPLLRAIIGAGLYPN 778
              ||:.:|                                 :|.:...:::.||:.::|.||||.
Mouse   747 GCSSDEEDREGSTSQRADSVDIQDVKFKLRHNLEQLQAAASSAQDLTRDQLALLKLVLGRGLYPQ 811

  Fly   779 MAHLRKSRQIKNRVRAIHTMATDDGRRVNFHPSSVNSGESGFDSAYFVYFQRQKSTDLFLLDSTM 843
            :|                            .|.:.|||..  ||....:.|.::.|   :|..|.
Mouse   812 LA----------------------------VPDAFNSGRK--DSDQIFHTQAKQGT---VLHPTC 843

  Fly   844 VF---PMALIIFG------DGVEAGVTQ----------------NTPYL--CV-----AKTYYFK 876
            ||   |..|...|      :|.:.|..|                |.|||  ||     .....|.
Mouse   844 VFANSPEVLHTQGQEASGQEGSQDGRDQMSCKHQLLAFVSLLETNKPYLVNCVRIPALQSLLLFS 908

  Fly   877 --------CNRETADVVIQLR---SNLEKLLLKKALYPAPIEENGYEKQLIK-AIELLLSLDERL 929
                    |:|..||..::|:   |.....||..:|......|:..::||.: |....|..:|.:
Mouse   909 RSIDTNGDCSRLVADGWLELQLADSESAVRLLATSLRLRVHWESALDRQLARQAQRRKLEQEEDM 973

  Fly   930 GEDYISSDEI 939
            |...:|..|:
Mouse   974 GSPAVSPQEV 983

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	188/508 (37%)
		OB_NTP_bind	767..856	CDD:400182	22/97 (23%)
Dhx34	NP_082159.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		8/42 (19%)
		HrpA	162..>628	CDD:441249	197/532 (37%)
		DEAH box	281..284		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	726..764		3/37 (8%)
		OB_NTP_bind	800..911	CDD:400182	32/143 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1091..1114