DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rhau and DHX33

DIOPT Version :10

Sequence 1:NP_610056.1 Gene:Rhau / 35339 FlyBaseID:FBgn0032883 Length:942 Species:Drosophila melanogaster
Sequence 2:NP_064547.2 Gene:DHX33 / 56919 HGNCID:16718 Length:707 Species:Homo sapiens


Alignment Length:61 Identity:17/61 - (27%)
Similarity:25/61 - (40%) Gaps:14/61 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   713 WCETREVNFLDQALADSSHPSEVGRCVQIGLLCVQHEPA----DRPNTLELLSMLTTTSDL 769
            |....:.||::    |.:|  :.|...|..:.|...|.|    ....||:||    |.:||
Human    42 WRGEFDANFIE----DLTH--KTGNFKQFSIFCNMLESALTQSSESVTLDLL----TYTDL 92

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhauNP_610056.1 HrpA 160..>664 CDD:441249
OB_NTP_bind 767..856 CDD:400182 2/3 (67%)
DHX33NP_064547.2 Required for nucleolar location. /evidence=ECO:0000269|PubMed:26100019 1..80 10/43 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..64 6/27 (22%)
HrpA 73..>700 CDD:441249 8/24 (33%)
DEAH box 194..197
HA2, required for interaction with EIF3G and RPL26. /evidence=ECO:0000269|PubMed:26100019 471..562
Critical for rDNA-binding. /evidence=ECO:0000250 547..558
Blue background indicates that the domain is not in the aligned region.

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