Protein Alignment Rhau and Tdrd9

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_017450003.1
• Gene: Tdrd9 / 299343
• RGDID: 1306942
• Length: 1396
• Species: Rattus norvegicus
• Alignment Length: 1004
• Identity: 270/1004 - (26%)
• Similarity: 434/1004 - (43%)
• Gaps: 240/1004 - (23%)

  Fly    60 APSGVLERVKELMEDYSRAPSRQNVDDKNVDAKFQQQFRHLLSVNFEEFVAETKERNADLDWVNP 124
            ||...::|.:|:.   |.||:.|..|.....|         |:.....|.....:|:::::::|.
  Rat    36 APREEVQRSEEVP---SEAPTAQAQDPVKATA---------LARPASAFGRSLSQRSSEVEYINK 88

  Fly   125 -KLDERLQLEL-GQRQLEENAKKRLEARK---------------KLPTMKYADDIIQAVRENQVI 172
             :..|..:|:: ||.|.......|....|               .||..:..:::|..:..|.|:
  Rat    89 YRQLEAQELDIYGQDQPPSGPGLRSPLAKISNVACIPETTYKYPDLPINRCKEEVISLIESNSVV 153

  Fly   173 LIVGSTGCGKTTQVPQILLDDAISRGCASSCRIICTQPRRISAIAIAEWVSYERCESLGNSVGYQ 237
            :|.|:||.||:||:||.:||....|  ::.|.|:.||||:|.|.:||.|:|.||..:||..||||
  Rat   154 IIHGATGSGKSTQLPQYVLDHYTQR--SAFCNIVVTQPRKIGASSIARWISKERSWTLGGLVGYQ 216

  Fly   238 IRLESRKARERASITYCTTGVLLQQLQSDPLMHNLSVLILDEIHERSVETD-LLMGLLKVILPHR 301
            :.|| :.|.|...:.|.|||||||::.|...:...:.:.:||:|||:.|.| ||:.:.|::..:.
  Rat   217 VGLE-KTATEDTRLIYMTTGVLLQKIVSAKSLMEFTHVFIDEVHERTEEMDFLLLVVRKLLRTNS 280

  Fly   302 PDLKVILMSATVREQDFCDYF--------NNCPMFRIEGVMFPVKMLYLEDVLSKTNYEFQKFRD 358
            ..:||||||||:..:.|.|||        |...:|.:||....::..||.|:    .:.:....
  Rat   281 RFVKVILMSATINCKQFADYFAVPVQNKMNPAYVFEVEGKPHTIEQYYLNDL----GHIYHSGL- 340

  Fly   359 RRPKRDPPERRMKHEAMIEPYLRRIRNSYDSRV-----LDKLRLPES-----EGCEDIDFIADLV 413
                  ||.|      :.||.:  .::.|:..|     .|.|.:.||     .|.:   |:::
  Rat   341 ------PPYR------LEEPVI--TKDVYEVAVSLIQMFDDLDMKESGNKTWSGAQ---FVSE-- 386

  Fly   414 YYICENEPEGAILVFLPGYDKISQLYNILDKPKTSKGQRWRDHMAVFPLHSLMQSGEQQAVFRRP 478
                    ..::||||||..:|:.::.:|.       ......:.|:||||.:...||..||..|
  Rat   387 --------RSSVLVFLPGLGEINYMHELLT-------NMIHKRLQVYPLHSSVTLEEQNNVFLSP 436

  Fly   479 PAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNIQSLDEVWVTKANTQQRRGRAGR 543
            ..|.||:|:||.|||:|||:.||.|||:...|:....|.:||.|||...|.:|.:..||:|||||
  Rat   437 VPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCDQRKGRAGR 501

  Fly   544 VRPGICYNLFSRARED-RMDDIPTPEILRSKLESIILSLKLLHIDDPYRFLQTLINAPNPEAIKM 607
            |..|.||.|..|...| .:.|...||:||..|.|.:|.:|||.:.:|...|.|.::.|:...|:.
  Rat   502 VSKGYCYRLIHRDFWDSAIPDHVVPEMLRCPLGSTVLKVKLLDMGEPRALLATALSPPSLSDIER 566

  Fly   608 GVELLKRIEAL-------DQT---GTLTPLGMHLAKLPIDPQMGKMILMSALFCCLDPITSAAAA 662
            .:.|||.:.||       |:.   |.||.||..||:||:..|:||:|::..:|.|||.....|||
  Rat   567 TILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVSQQLGKLIVLGHVFGCLDECLIIAAA 631

  Fly   663 LSFKSPFYSPLGKESRVDEIKRRMARNMRSDHLMVHNTIIAYR------DSRYSHAERDFCYKNF 721
            ||.|:.|..|..:.......|...:.:.|||.|.:.....|::      :.|:...|.|:...|:
  Rat   632 LSLKNFFTMPFRQHLDGYRNKVHFSGSSRSDCLALVEAFRAWQACRQRGELRHPKDELDWGRLNY 696

  Fly   722 LSSMTLQQL----ERMKNQFS---------------ELLYNYKFLASSNCKDAASNKNSEKIPLL 767
            :....::::    |.:||:.|               |..|..:|                   :|
  Rat   697 IQIKRIREVAELYEELKNRISQFNMFVDPRHPVLDQEYPYKQRF-------------------IL 742

  Fly   768 RAIIGAGLYPN--------------------------MAHL---------------RKSRQIKNR 791
            :.::....|||                          :.|:               |:..|:|:.
  Rat   743 QVVLAGAFYPNYFTFGQPDEEMAVRELAGRDPKTTVVLKHIPPYGFLYYKQLQSLFRQCGQVKSI 807

  Fly   792 V--------------------------------------RAIHTMATDDGRRVNFHPSSVNSGES 818
            |                                      .:||.....:|:......|.:.:...
  Rat   808 VFDGAKAFVEFSRNPTERFKTLPAVNLAVKMSQLKVSLELSIHAAEEIEGKVQGGSVSKLRNTRV 872

  Fly   819 GFDSAYFVYFQRQKSTDLFLLDSTMVFPMA---LIIFGDGVEAGVTQNTPYLCVAKTYYF---KC 877
            ..|      ||:|....:.:..:|:..|..   |::..|..|..:..:|..|.|.:..:|   :.
  Rat   873 NVD------FQKQTVDPMQVSFNTLDRPRTVADLLLTVDVTEVALCAHTLLLQVVEVGHFWGYRI 931

  Fly   878 NRETADVVIQLRSNLEKLLLKKALYPAPI 906
            :...|:::.||.:.:.:|    .|.|.||
  Rat   932 DERNAELLRQLTAEINRL----ELVPLPI 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	191/533 (36%)
		OB_NTP_bind	767..856	CDD:400182	21/170 (12%)
Tdrd9	XP_017450003.1	HrpA	132..>707	CDD:441249	208/616 (34%)
		DEAD-like_helicase_N	134..317	CDD:475120	75/185 (41%)
		Tudor_TDRD9	919..1018	CDD:410502	10/42 (24%)