Protein Alignment Rhau and Dhx15

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001178526.1
• Gene: Dhx15 / 289693
• RGDID: 1308072
• Length: 795
• Species: Rattus norvegicus
• Alignment Length: 924
• Identity: 271/924 - (29%)
• Similarity: 419/924 - (45%)
• Gaps: 161/924 - (17%)

  Fly     2 QRDRDSSGSNARKGNRPPGLRGK----DIGLYYRNLARQQKKDRG----ENAESKEPQIRLGCNV 58
            :|.|...|.:...|.:..|..||    |.....|:..|.:::|||    |..:.||.::|...|.
  Rat     3 KRHRLDLGEDYPSGKKRAGTDGKDRERDRDREDRSKDRDRERDRGDREREREKEKEKELRASTNA 67

  Fly    59 SAPSGVLERVKELMEDYSRAPSRQNVDDKNVDAKFQQQFRHL---LSVNFEEFVAETKERNADLD 120
            ...|..|..:|.....:|...:.......:..:.......|.   ..:|....:..|
  Rat    68 MLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHTGHAGHTSLPQCINPFTNLPHT-------- 124

  Fly   121 WVNPKLDERLQLELGQRQLEENAKKRLEARKKLPTMKYADDIIQAVRENQVILIVGSTGCGKTTQ 185
               |:..:.|             ||||:    ||..:|.|.....:..:|..::||.||.|||||
  Rat   125 ---PRYYDIL-------------KKRLQ----LPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQ 169

  Fly   186 VPQILLDDAIS-----RGCASSCRIICTQPRRISAIAIAEWVSYERCESLGNSVGYQIRLESRKA 245
            :||..::...|     ||.|      ||||||::|:::|:.|:.|....||..|||.||.|...:
  Rat   170 IPQWCVEYMRSLPGPKRGVA------CTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSS 228

  Fly   246 RERASITYCTTGVLLQQLQSDPLMHNLSVLILDEIHERSVETDLLMGLLKVILPHRPDLKVILMS 310
             .:..:.|.|.|:||::..:|||:....|:||||.|||::.||:|||:||.::..|.|||||:||
  Rat   229 -AKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMS 292

  Fly   311 ATVREQDFCDYFNNCPMFRIEGVMFPVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAM 375
            ||:....|..||:|||:..|.|...||::.|..:                |:||          .
  Rat   293 ATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPE----------------PERD----------Y 331

  Fly   376 IEPYLRRIRNSYDSRVLDKLRLPESEGCEDIDFIADLVYYICENEPEGAILVFLPGYDKISQLYN 440
            :|..:|.:                            :..::||.| ||.:|:||.|.::|.:...
  Rat   332 LEAAIRTV----------------------------IQIHMCEEE-EGDLLLFLTGQEEIDEACK 367

  Fly   441 ILDKPKTSKGQRWRDHMAVFPLHSLMQSGEQQAVFRRPP------AGQRKVIISTIIAETSVTID 499
            .:.:.....|....| :.:.||:|.:...:||.:|..||      |..|||::||.|||||:|||
  Rat   368 RIKREVDDLGPEVGD-IKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTID 431

  Fly   500 DVVYVINSGRTKATNYDIETNIQSLDEVWVTKANTQQRRGRAGRVRPGICYNLFS-RAREDRMDD 563
            .||:||:.|..|...|:....::||....::||:.|||.|||||.|||.|:.|:: :|.:..|.|
  Rat   432 GVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQD 496

  Fly   564 IPTPEILRSKLESIILSLKLLHIDDPYRFLQTLINAPNPEAIKMGVELLKRIEALDQTGTLTPLG 628
            ...||||||.|.|::|.||.|.|||...|  ..::.|.||.:...:|||..:.||:..|.||.||
  Rat   497 NTYPEILRSNLGSVVLQLKKLGIDDLVHF--DFMDPPAPETLMRALELLNYLAALNDDGDLTELG 559

  Fly   629 MHLAKLPIDPQMGKMILMSALFCCLDPITSAAAALSFKSPFYSPLGKESRVDEIKRRMARNMRSD 693
            ..:|:.|:|||:.||::.|..:.|.:.:.|..|.||....|..|...:...||.|.|.| ::..|
  Rat   560 SMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAADEAKMRFA-HIDGD 623

  Fly   694 HLMVHNTIIAYRDSRYSHAERDFCYKNFLSSMTLQQLERMKNQFSELLYNYKFLASS---NCKDA 755
            ||.:.|...|::.   :|....:||.||::..:|...:.::.|.|.::..:.....|   ..:|.
  Rat   624 HLTLLNVYHAFKQ---NHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDY 685

  Fly   756 ASNKNSEKIPLLRAIIGAGLYPNMAHLRKSRQIKNRVRAIHTMATDDGRRVNFHPSSVNSGESGF 820
            ..|        :|..:..|.:..:|||.         |..|.:...|.:.|..|||:|...:
  Rat   686 YIN--------IRKALVTGYFMQVAHLE---------RTGHYLTVKDNQVVQLHPSTVLDHK--- 730

  Fly   821 DSAYFVYFQRQKSTDLFLLDSTMVFPMALIIFGDGVEAGVTQNTPYLCVAKTYYFKCNRETADVV 885
             ..:.:|.:...:|..::...|.:.|..|:                 .:|..||...|....:..
  Rat   731 -PEWVLYNEFVLTTKNYIRTCTDIKPEWLV-----------------KIAPQYYDMSNFPQCEAK 777

  Fly   886 IQLRSNLEKLLLKK 899
            .||...:.||..|:
  Rat   778 RQLDRIIAKLQSKE 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	185/515 (36%)
		OB_NTP_bind	767..856	CDD:400182	18/88 (20%)
Dhx15	NP_001178526.1	HrpA	136..>763	CDD:441249	231/737 (31%)