Protein Alignment Rhau and Dhx8

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_001400156.1
• Gene: Dhx8 / 287727
• RGDID: 1310723
• Length: 1242
• Species: Rattus norvegicus
• Alignment Length: 911
• Identity: 263/911 - (28%)
• Similarity: 425/911 - (46%)
• Gaps: 164/911 - (18%)

  Fly    10 SNARKGNRPPGL------RGKDIGLYYRNLARQQKKDRGE-------NAESKE--PQIRLGCNVS 59
            ::.|..:||..|      ..:|..|..:.|.|....::.|       |..|||  |      :..
  Rat   384 TSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKEEFP------DFD 442

  Fly    60 APSGVLERVK---------ELMED---YSRAPSRQNVD------DKNVDAKFQQQFRHLLSVNFE 106
            ..:|:|.:|.         ||:|:   :.|..::|::|      .||.|....|......::..|
  Rat   443 EETGILPKVDDEEDEDLEIELVEEEPPFLRGHTKQSMDMSPIKIVKNPDGSLSQAAMMQSALAKE 507

  Fly   107 EFVAETKERNADLD---------WVNPKLD-ERLQLELGQRQL---------------------- 139
            ....:..:|.|::|         ||:|..| |..|:....|.:
  Rat   508 RRELKQAQREAEMDSIPMGLNKHWVDPLPDAEGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASY 572

  Fly   140 -EENAKKRLEARKKLPTMKYADDIIQAVRENQVILIVGSTGCGKTTQVPQILLDDAISRGCASSC 203
             ::.....||.|:.||..|..:.::|||.:||:::::|.||.|||||:.|.|.:    .|..|..
  Rat   573 GKKTQMSILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAE----AGYTSRG 633

  Fly   204 RIICTQPRRISAIAIAEWVSYERCESLGNSVGYQIRLESRKARERASITYCTTGVLLQQLQSDPL 268
            :|.||||||::|:::|:.||.|....||..|||.||.|...:.|.. |.|.|.|:||::...||.
  Rat   634 KIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETV-IKYMTDGMLLRECLIDPD 697

  Fly   269 MHNLSVLILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSATVREQDFCDYFNNCPMFRIEGV 333
            :...::::|||.|||::.||:|.||||..:..|.|:|:|:.|||:....|..||...|:|.|.|.
  Rat   698 LTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGR 762

  Fly   334 MFPVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNSYDSRVLDKLRLP 398
            .:||::||.::                |:.|              ||
  Rat   763 TYPVEILYTKE----------------PETD--------------YL------------------ 779

  Fly   399 ESEGCEDIDFIADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPKTSKGQRWRDHMAVFPLH 463
                  |...|.  |..|...||.|.|||||.|.::|.....||.:...|.|....: :.:.|::
  Rat   780 ------DASLIT--VMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPE-LIILPVY 835

  Fly   464 SLMQSGEQQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNIQSLDEVW 528
            |.:.|..|..:|...|.|.|||:|:|.|||||:|||.:.||::.|..|...|:.:|.|..|....
  Rat   836 SALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTP 900

  Fly   529 VTKANTQQRRGRAGRVRPGICYNLFS-RAREDRMDDIPTPEILRSKLESIILSLKLLHIDDPYRF 592
            :::|..:||.|||||..||.||.|:: ||..|.|.....|||.|:.|.|.:||||.:.|:|...|
  Rat   901 ISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSF 965

  Fly   593 LQTLINAPNPEAIKMGVELLKRIEALDQTGTLTPLGMHLAKLPIDPQMGKMILMSALFCCLDPIT 657
              ..::||..|.:...:|.|..:.|||..|.||.||..:|:.|::|.:.||::||....|.:.:.
  Rat   966 --DFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEML 1028

  Fly   658 SAAAALSFKSPFYSPLGKESRVDEIKRRMARNMRSDHLMVHNTIIAYRDSRYSHAERDFCYKNFL 722
            :..:.||.::.||.|..|::..|: |:........|||.:.....:::::::|:   .:||:||:
  Rat  1029 TIVSMLSVQNVFYRPKDKQALADQ-KKAKFHQTEGDHLTLLAVYNSWKNNKFSN---PWCYENFI 1089

  Fly   723 SSMTLQQLERMKNQFSELLYNYKFLASSNCKDAAS-NKNSEKIPLLRAIIGAGLYPNMAHLRKSR 786
            .:.:|::.:.::.|...::..:|.       |..| .|::.::   :..|.:|.:.|.|.
  Rat  1090 QARSLRRAQDIRKQMLGIMDRHKL-------DVVSCGKSTVRV---QKAICSGFFRNAAK----- 1139

  Fly   787 QIKNRVRAIHTMATDDGRRVNFHPSSVNSGESGFDSAYFVYFQRQKSTDLFLLDSTMVFPMALII 851
              |:......|:.  |.:.|..||||.....   ...:.||.:...:|..::.:.|.:.|..|:.
  Rat  1140 --KDPQEGYRTLI--DQQVVYIHPSSALFNR---QPEWVVYHELVLTTKEYMREVTTIDPRWLVE 1197

  Fly   852 F 852
            |
  Rat  1198 F 1198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	178/504 (35%)
		OB_NTP_bind	767..856	CDD:400182	19/86 (22%)
Dhx8	NP_001400156.1	GH2-like_DHX8	25..92	CDD:409668
		S1_DHX8_helicase	287..365	CDD:240189
		HrpA	578..>1204	CDD:441249	225/711 (32%)