Protein Alignment Rhau and cdc28

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_595686.2
• Gene: cdc28 / 2540707
• PomBaseID: SPBC19C2.01
• Length: 1055
• Species: Schizosaccharomyces pombe
• Alignment Length: 947
• Identity: 263/947 - (27%)
• Similarity: 429/947 - (45%)
• Gaps: 194/947 - (20%)

  Fly    10 SNARKGNRPPGLRGK---DIGLYYRNLARQQKKDRGE---NAESKEPQIRLGCNVSAPSGVLERV 68
            |..||.:|...|:.:   .:.:..|.:..:::...||   .||.:|               ||:.
pombe   233 SELRKKSRQQYLKPRAQQQLEILRREIRDEEQLFAGEKLTQAEIRE---------------LEKK 282

  Fly    69 KELM-------------------EDYSRAPSRQNVDDKNVDAKFQQQFRHLLSVNFEEFVA---- 110
            |||:                   |||.....:  :|.|..:....|:::........|...
pombe   283 KELLRIAEERQRLEKQATEYQMPEDYFTEQGK--LDRKRKEEVLYQRYKDSNEGEQNEVTMGAAE 345

  Fly   111 ----ETKERNADL-----DWVNP-------KLDERLQLE--LGQRQLEEN-----------AKKR 146
                |.::.|..|     :|:.|       ..||..|::  |..:...||           .:|.
pombe   346 QQRWEAQQINKALLFDQNEWLPPGEKQFDFVFDESQQIDFLLDTKLSAENPVDTDKMTDVKVEKS 410

  Fly   147 LE-ARKKLPTMKYADDIIQAVRENQVILIVGSTGCGKTTQVPQILLDDAISRGCASSCRIICTQP 210
            || :||.||..:|.||:::|:.|.||:|||..||.|||||:||.|.:...::|   :.:|.||||
pombe   411 LESSRKSLPVYQYKDDLLKAINEYQVLLIVAETGSGKTTQLPQFLHEAGYTKG---NKKICCTQP 472

  Fly   211 RRISAIAIAEWVSYERCESLGNSVGYQIRLESRKARERASITYCTTGVLLQQLQSDPLMHNLSVL 275
            ||::|:::|..|:.|....||..|||.||.|:..: |:..|.|.|.|:||::..::|.:.:.||:
pombe   473 RRVAAMSVAARVAKEMDVRLGQEVGYSIRFENATS-EKTVIKYLTDGMLLREFLTEPDLASYSVI 536

  Fly   276 ILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSATVREQDFCDYFNNCPMFRIEGVMFPVKML 340
            |:||.|||::.||:|.||:|.|...||||||::.|||:..:.|..||:..|:|.:.|..:||.:.
pombe   537 IIDEAHERTLHTDILFGLVKDIARFRPDLKVLISSATIDAEKFSAYFDEAPVFYVPGRRYPVDIY 601

  Fly   341 YLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNSYDSRVLDKLRLPESEGCED 405
            |...  .:.||
pombe   602 YTPQ--PEANY------------------------------------------------------ 610

  Fly   406 IDFIADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPKTSKGQRWRDHMAVFPLHSLMQSGE 470
            |......:..|...:|.|.|||||.|.|:|..:...:.:.....|:|..: :.:.|:::.:.|..
pombe   611 IQAAITTILQIHTTQPAGDILVFLTGQDEIELMSENMQELCRILGKRIPE-IILCPIYANLPSEL 674

  Fly   471 QQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNIQSLDEVWVTKANTQ 535
            |..:|...|.|.|||:::|.|||||:|||.|.:||:||..|...|:..|.::||..|..::|:..
pombe   675 QAKIFDPTPPGARKVVLATNIAETSITIDGVNFVIDSGFVKQNMYNPRTGMESLVSVPCSRASAD 739

  Fly   536 QRRGRAGRVRPGICYNLFS-RAREDRMDDIPTPEILRSKLESIILSLKLLHIDDPYRFLQTLINA 599
            ||.||||||.||.|:.|:: |...:.:|.:.:|||.|:.|.:|:|.||.|.|::...|  ..::|
pombe   740 QRAGRAGRVGPGKCFRLYTRRTYNNELDMVTSPEIQRTNLTNIVLLLKSLGINNLLDF--DFMDA 802

  Fly   600 PNPEAIKMGVELLKRIEALDQTGTLTPLGMHLAKLPIDPQMGKMILMSALFCCLDPITSAAAAL- 663
            |.||.:...:|||..:.||:..|.||.||..:|:.|.||.:.|.::.|:.:.|::.:.|..:.|
pombe   803 PPPETLMRSLELLYALGALNNRGELTKLGRQMAEFPTDPMLSKSLIASSKYGCVEEVLSIVSMLG 867

  Fly   664 SFKSPFYSPLGKESRVDEIKRRMARNMRSDHLMVHNTIIAYRDSRYSHAERDFCYKNFLSSMTLQ 728
            ...|.||.|..|....|:.:....: ...|||.:.:....:.|:.:|:   ::..:|||...:|.
pombe   868 EASSLFYRPKDKIMEADKARANFTQ-PGGDHLTLLHIWNEWVDTDFSY---NWARENFLQYKSLC 928

  Fly   729 QLERMKNQFSELLYNYKFLASSNCKDAASNKNSEKIPLLRAIIGAGLYPNMAHLRKSRQIKNRVR 793
            :...:::|.:.|....:....:|        :||.:..::..|.||.:.|.|.|.:|......|:
pombe   929 RARDVRDQLANLCERVEIELVTN--------SSESLDPIKKAITAGYFSNAARLDRSGDSYRTVK 985

  Fly   794 AIHTMATDDGRRVNFHPSSVNSGESGFDSAYFVYFQRQKSTDLFLLDSTMVFPMALIIFGDGVEA 858
            :..|        |..||||..:.:.   ....:||:...:|..:....|.:.|
pombe   986 SNQT--------VYIHPSSSVAEKK---PKVIIYFELVLTTKEYCRQITEIQP------------ 1027

  Fly   859 GVTQNTPYLCVAKTYYFKCNRETADVVIQLRSNLEKL 895
                  .:|.....:|||            ..|:|:|
pombe  1028 ------EWLLEISPHYFK------------PENIEEL 1046

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	175/505 (35%)
		OB_NTP_bind	767..856	CDD:400182	19/88 (22%)
cdc28	NP_595686.2	PTZ00121	<68..>357	CDD:173412	25/140 (18%)
		DUF4670	<213..322	CDD:464815	21/105 (20%)
		HrpA	417..>1039	CDD:441249	219/725 (30%)