Protein Alignment Rhau and prp16

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_595890.2
• Gene: prp16 / 2540006
• PomBaseID: SPBC1711.17
• Length: 1173
• Species: Schizosaccharomyces pombe
• Alignment Length: 983
• Identity: 261/983 - (26%)
• Similarity: 424/983 - (43%)
• Gaps: 235/983 - (23%)

  Fly    39 KDRGENAESKEPQIR-LGCNVS---APSGVLERVKELMEDYSRAPSRQN----VDDKNVDAKFQQ 95
            :||...||..|.|.: |....|   ..:.:.|:.:.:....|:||..::    ::::.|.....:
pombe   314 EDRAHEAEFIEKQKKHLSIEASDRFKENSMWEKNRMITSGVSKAPGLESDYSLMEERRVHLLVDE 378

  Fly    96 QFRHLLSVNFEEF-------VAETKERNADLDWVNPKLDERL---QLELGQRQ------------ 138
            ...|.|  :..||       :...::..:||. :|.:|..||   :.|..:||
pombe   379 LRPHFL--DGAEFSSKKVGDITSVRDPQSDLA-INARLGSRLVRERREFRERQKAASAATSLAGT 440

  Fly   139 ----------------------------LEENAKKRLE-ARKK--------LPTMKYADDIIQAV 166
                                        .|::.||..| ||.|        ||.....:.::..:
pombe   441 SLGNVMGLKDSNDEDAKAGTTPVKVAGRSEQSNKKDTEFARTKSYREQREFLPAFAVREQLLSVI 505

  Fly   167 RENQVILIVGSTGCGKTTQVPQILLDDAISRGCASSCRIICTQPRRISAIAIAEWVSYERCESLG 231
            |:|||:::||.||.|||||:.|.|.:|...|    :..|.||||||::|:::|:.||.|....||
pombe   506 RDNQVLIVVGETGSGKTTQLAQFLYEDGYHR----NGMIGCTQPRRVAAMSVAKRVSEEMGVRLG 566

  Fly   232 NSVGYQIRLESRKARERASITYCTTGVLLQQLQSDPLMHNLSVLILDEIHERSVETDLLMGLLKV 296
            ::|||.||.|.....:.. |.|.|.||||::......:...||:|:||.||||:.||:||||||.
pombe   567 STVGYSIRFEDVTGPDTV-IKYMTDGVLLRESLMQNNLEKYSVIIMDEAHERSLNTDILMGLLKK 630

  Fly   297 ILPHRPDLKVILMSATVREQDFCDYFNNCPMFRIEGVMFPVKMLYLEDVLSKTNYEFQKFRDRRP 361
            :|..|.|:|:::.|||:..|.|.|:|...|.|.|.|..:||.:::.                :.|
pombe   631 VLSRRRDIKLLVTSATMNSQKFSDFFGGAPQFTIPGRTYPVDIMFA----------------KAP 679

  Fly   362 KRDPPERRMKHEAMIEPYLRRIRNSYDSRVLDKLRLPESEGCEDIDFIADLVYYICENEPEGAIL 426
            ..|          .:|..:|:                              |..|..::|.|.||
pombe   680 CSD----------YVEAAVRQ------------------------------VLQIHLSQPAGDIL 704

  Fly   427 VFLPGY-----------DKISQLYNILDKPKTSKGQRWRDHMAVFPLHSLMQSGEQQAVFRRPPA 480
            ||:.|.           |:::||:   |.|:          :::.|::|.|.:..|..:|.....
pombe   705 VFMTGQEDIEATCEIIADRLNQLH---DAPR----------LSILPIYSQMPADLQAKIFDSAEP 756

  Fly   481 GQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNIQSLDEVWVTKANTQQRRGRAGRVR 545
            |.|||:::|.|||||:|:..:.||:::|..|...|:.:..|.:|....:::||..||.|||||..
pombe   757 GVRKVVVATNIAETSLTVHGISYVVDTGYCKLKMYNSKLGIDTLQVTPISQANANQRAGRAGRTG 821

  Fly   546 PGICYNLFSRAREDR-MDDIPTPEILRSKLESIILSLKLLHIDDPYRFLQTLINAPNPEAIKMGV 609
            |||.|.|::.....| |.:...|||.|:.|.:.:|.||.|.:::...|  ..::.|..:.:...:
pombe   822 PGIAYRLYTEMAYIREMFETTLPEIQRTNLSNTVLILKSLGVEEISDF--DFMDRPPNDTLMASL 884

  Fly   610 ELLKRIEALDQTGTLTPLGMHLAKLPIDPQMGKMILMSALFCCLDPITSAAAALSFKSPFYSPLG 674
            ..|..:.|||..|.||.||..::..|:||.:.|:|:::..:.|.:.|.:..:.||..|.||.|..
pombe   885 YELWTLGALDNFGKLTTLGKKMSLFPMDPSLSKLIIIAEDYKCTEEIITIVSMLSVPSVFYRPKE 949

  Fly   675 KESRVDEIKRRMARNM-RSDHLMVHNTIIAYRDSRYSHAERDFCYKNFLSSMTLQQLERMKNQFS 738
            :....|..:.:.  |: .|||||:.|....::.:.||::   :|.|:||.|.||::...::.|..
pombe   950 RAEESDAAREKF--NVPESDHLMLLNIYQHWQRNGYSNS---WCSKHFLHSKTLKRARDIRQQLV 1009

  Fly   739 ELLYNYKF--------------LASSNCKDAASNKNSEKIPLLRAIIGAGLYPNMAHLRKSRQIK 789
            |::...|.              |.|:....||..|            |.|.|   .|||
pombe  1010 EIMSKQKISLESVSDWDIVRRVLCSAYFHQAACAK------------GIGEY---VHLR------ 1053

  Fly   790 NRVRAIHTMATDDGRRVNFHPSSVNSGESGFDSAYFVYFQRQKSTDLFLLDSTMVFPMALIIFGD 854
                        .|...:.|.:|...| .|:...|.:|.:...::..::...|.|.|..|..||
pombe  1054 ------------SGMPCHLHVTSSLYG-LGYLPDYVIYHELVLTSKEYMNIVTSVDPYWLAEFG- 1104

  Fly   855 GVEAGVTQNTPYLCVAKTYYFKCNRETADVVIQLRSNLEKLLL---------KKALYPAPIEENG 910
            ||...|.:.           |:...|:.|.|...:..|:..:.         |.|....|::..
pombe  1105 GVYYSVKER-----------FRNETESYDRVFSSKPQLDAQIAADRELDAKQKLAKNQEPVKSK- 1157

  Fly   911 YEKQLIKA 918
             .|.:|:|
pombe  1158 -RKSVIRA 1164

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	162/515 (31%)
		OB_NTP_bind	767..856	CDD:400182	19/88 (22%)
prp16	NP_595890.2	HrpA	492..>1087	CDD:441249	208/709 (29%)