Protein Alignment Rhau and rha-2

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: NP_498895.1
• Gene: rha-2 / 176207
• WormBaseID: WBGene00015525
• Length: 1148
• Species: Caenorhabditis elegans
• Alignment Length: 862
• Identity: 225/862 - (26%)
• Similarity: 376/862 - (43%)
• Gaps: 163/862 - (18%)

  Fly    47 SKEPQIRLGCNVSAP---------SGVLE-RVKELMEDYSRAPSRQNVDDKNVDAKFQQQFRHLL 101
            ||||:       .||         ||..: ..|...:||      ...||::...:.:::.....
 Worm   105 SKEPE-------KAPVFPEKLKVFSGKTKTEAKRTQQDY------YPTDDESSSEEEEEEEEGDN 156

  Fly   102 SVNFEEFVAETKERNADLDWVNPKLDERLQLELGQ----------------------------RQ 138
            .:.......|.|....|||.|:..:|...:..|.|                            :.
 Worm   157 DIEDAGNTVEVKIEPIDLDDVDEAIDGNPETNLDQIVVKREDDEESDNEDILALPTTTVINRKKV 221

  Fly   139 LEENAKKRLEARKKLPTMKYADDIIQAVRENQVILIVGSTGCGKTTQVPQILLDDAISRGCASSC 203
            :.|.:|:..::|.:||.......|::|:.||.|.::.|.||.|||||:||.|.:    .|.||..
 Worm   222 IVERSKEIQKSRAELPIFAEEMRIVEAINENLVTVVCGETGSGKTTQIPQFLYE----AGYASEG 282

  Fly   204 RII-CTQPRRISAIAIAEWVSYERCESLGNSVGYQIRLESRKARERASITYCTTGVLLQQLQSDP 267
            .:| .|:|||::|||:|:.|..|..:.  :.|.||||.|..:: |..:|.:.|.|||:::::.|.
 Worm   283 ELIGITEPRRVAAIAMAQRVGVELAKP--DEVSYQIRYEGTRS-ETTNILFMTDGVLMKEMEQDV 344

  Fly   268 LMHNLSVLILDEIHERSVETDLLMGLLKVILPHRP----DLKVILMSATVREQDFCDYFNNCPM- 327
            ::...||:::||.||||:.:|:|:|:|..|:|.|.    .|::::||||:|..|| .:....|:
 Worm   345 MLKKYSVILIDEAHERSMYSDVLIGMLSRIVPLRSKTARPLRLVIMSATLRLDDF-THKKLFPLL 408

  Fly   328 ----FRIEGVMFPVKML--------YLEDVLSKT------------------NYEFQKFRDRRPK 362
                .:::...|||.:.        |:.....||                  .:|.::...:..|
 Worm   409 TPKVIKVDARQFPVSVHFEKRTPDDYIASAFRKTCRIHETLPPGAILVFVTGQHEVKQLITKLKK 473

  Fly   363 RDPP--ERRMKHEAMI----EPYLRRIRNSYDSRVLD-KLRLPESEGCEDIDFIADLVYYICENE 420
            |.|.  |.....|.::    |...:::..:...::.| |...||:|..||:|   |.:....:..
 Worm   474 RYPVVYETDKNGEVLVKGTKEWKEKKVEAAKSIKLEDFKEETPETEDFEDVD---DGLMDGDDMN 535

  Fly   421 PEGAILVFLPGYDKISQLYN----ILD-KPKTSKGQRWRDHMAVF--PLHSLMQSGEQQAVFRRP 478
            ..||...|    |...:..|    :.| |.:.|.|....|...::  ||:||:..|:|:.||...
 Worm   536 ERGAAEAF----DDYEEFENGDGDLSDGKVENSIGAPPADCEPLYCLPLYSLLSMGKQRRVFDET 596

  Fly   479 PAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNIQSLDEVWVTKANTQQRRGRAGR 543
            |||.|..:|||.:||||:||..|.|||:.|..|...||..|.:.......:::|:..||.|||||
 Worm   597 PAGMRLCVISTNVAETSLTIPGVKYVIDGGFEKRRLYDSITGVSRFAVCRISQASGDQRAGRAGR 661

  Fly   544 VRPGICYNLFSRAREDRMDDIPTPEILRSKLESIILSLKLLHIDDPYRFLQTLINAPNPEAIKMG 608
            :..|..|.|:|.|..........||||....:.::|.||.::|.....|  ...:||:.:.::..
 Worm   662 ISAGHAYRLYSSAVYQDFVKFADPEILSKPADQLVLHLKSMNIVKVVNF--PFPSAPDEQMLESA 724

  Fly   609 VELLKRIEALDQT-------GTLTPLGMHLAKLPIDPQMGKMILMSALFCCLDPITSAAAALSFK 666
            .:.|.|:.||.::       ..:|.||..||..|:.|...|.|.|:.....:.......:.||.:
 Worm   725 EKRLCRLGALSESTKNGKTEARITKLGKTLAVFPLAPSYAKFIAMADQHNLMSHAILLISLLSVR 789

  Fly   667 SPFYSPLG----------KESRVDEIKRRM-------ARNMRSDHLMVHNTIIAYRDSRYSHAER 714
            .|.. |:.          ||...:.:|.|.       ||.:....:::|...:| ...:|:..|
 Worm   790 EPLI-PVSSLRGDTPEETKELMKNVLKERRRWCSHTGARRLGDLKVLMHAASVA-EQIKYNARE- 851

  Fly   715 DFCYKNFLSSMTLQQLERMKNQFSELLYNYKFLASSNC-KDAASNKNSEKIP-------LLRAII 771
              |.|..|....|.:..:::.|.:.::       :::| |:.|:..:|:..|       |||.::
 Worm   852 --CEKVGLRVKALVEARKLRQQLTNIV-------NASCKKEHAAALDSDLPPPTDQQAQLLRQMV 907

  Fly   772 GAGLYPNMAHLRKSRQI 788
            .|.....:|. |..|.:
 Worm   908 VASFSDRLAR-RVDRSV 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	167/560 (30%)
		OB_NTP_bind	767..856	CDD:400182	6/22 (27%)
rha-2	NP_498895.1	HrpA	234..>1020	CDD:441249	200/720 (28%)