Protein Alignment Rhau and l(2)37Cb

DIOPT Version :10

• Sequence 1: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Sequence 2: XP_319843.5
• Gene: l(2)37Cb / 1280046
• VectorBaseID: AGAMI1_007561
• Length: 891
• Species: Anopheles gambiae
• Alignment Length: 809
• Identity: 238/809 - (29%)
• Similarity: 387/809 - (47%)
• Gaps: 125/809 - (15%)

  Fly    33 LARQQKKDRGENAESKEPQIRLGCNVSAPSGVLERV----------KELMEDYSRAPSRQNV--- 84
            :..::::||    |.|:..:::..: ...:..||||          |..||:|.....|:.:
Mosquito   111 ITERERRDR----EHKKRLLQIAKD-HEKARELERVQRYRMPKDVKKGEMEEYVEVDERERMPHS 170

  Fly    85 DDKNVDAKFQQQFRHLLSVNFEEFVAETKERNADLDWVNPKLDERLQ----LELG-------QRQ 138
            :.|..:|:      .|.|..:.....:.|||.|........|||::.    |::.       :.:
Mosquito   171 EQKKWEAE------QLASAVYGFGSKDAKERAAQQQEYELLLDEQIDFVEALQMAGTKKKDDKPE 229

  Fly   139 LEENAKKRL---EARKKLPTMKYADDIIQAVRENQVILIVGSTGCGKTTQVPQILLDDAISRGCA 200
            |.|..:|::   |.:|.||...:.:|:|.|::.:.:::|.|.||.|||||:||.|.:...:.
Mosquito   230 LTEAQRKKMTIEETQKSLPIYPFKEDLIAAIQAHNILIIEGETGSGKTTQIPQYLYEAGFTN--- 291

  Fly   201 SSCRIICTQPRRISAIAIAEWVSYERCESLGNSVGYQIRLESRKARERASITYCTTGVLLQQLQS 265
            ...:|.||||||::|:::|..|:.|....|||.|||.||.|...: ||..|.|.|.|.|.::..|
Mosquito   292 EGKKIGCTQPRRVAAMSVAARVAEEMAVKLGNEVGYSIRFEDCTS-ERTVIKYMTDGTLHREFLS 355

  Fly   266 DPLMHNLSVLILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSATVREQDFCDYFNNCPMFRI 330
            :|.:.:.:|:|:||.|||::.||:|.||:|.|...|.|||:::.|||:..:.|.|:|:..|:|||
Mosquito   356 EPDLASYAVMIIDEAHERTLHTDILFGLVKDIARFRKDLKLLISSATLDAEKFSDFFDKAPIFRI 420

  Fly   331 EGVMFPVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNSYDSRVLDKL 395
            .|..:||.:.|                                                     .
Mosquito   421 PGRRYPVDIFY-----------------------------------------------------T 432

  Fly   396 RLPESEGCEDIDFIADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPKTSKGQRWRDHMAVF 460
            :.||:   :.||.....|..|...:|.|.|||||.|.::|.....:|.......|.:.:: :.:.
Mosquito   433 KAPEA---DYIDACVVSVLQIHATQPLGDILVFLTGQEEIEACQEMLQDRVKRLGSKLKE-LLIL 493

  Fly   461 PLHSLMQSGEQQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNIQSLD 525
            |:::.:.|..|..:|...|...||||::|.|||||:|||:::|||:.|..|..|::..|.:::|.
Mosquito   494 PIYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMETLL 558

  Fly   526 EVWVTKANTQQRRGRAGRVRPGICYNLFSR-AREDRMDDIPTPEILRSKLESIILSLKLLHIDDP 589
            .|.::||:..||.||||||.||.|:.|::. |..:.::|...|||.|..|.:.:|.||.|.|.|.
Mosquito   559 VVPISKASANQRAGRAGRVAPGKCFRLYTAWAYNNELEDNTVPEIQRINLGNAVLMLKTLGIHDL 623

  Fly   590 YRFLQTLINAPNPEAIKMGVELLKRIEALDQTGTLTPLGMHLAKLPIDPQMGKMILMSALFCCLD 654
            ..|  ..::.|..:.:.:.:|.|..:.||:..|.||.||..:|:.|:||.|.||:|.|..:.|.:
Mosquito   624 LHF--DFLDPPPHQTLILALEQLYALGALNHHGELTKLGRRMAEFPVDPMMAKMLLASEKYKCSE 686

  Fly   655 PITSAAAALSFKSP-FYSPLGKESRVDEIKRRMARNMRSDHLMVHNTIIAYRDSRYSHAERDFCY 718
            .|.|.||.||.... ||.|..|....|..::.. .:...|||.:......:.:|.||   ..:||
Mosquito   687 EIVSIAAMLSVNGAIFYRPKDKIIHADTARKNF-NHRHGDHLSLMQVYNQWVESDYS---TQWCY 747

  Fly   719 KNFLSSMTLQQLERMKNQFSELLYNYKFLASSNCKDAASNKNSEKIPLLRAIIGAGLYPNMAHLR 783
            :||:...::::...::.|...|:...:....|...|..:         :|..|.||.:.::|.|.
Mosquito   748 ENFIQYRSMKRARDVREQLVGLMQRVEIEMVSGESDTTN---------VRKAITAGYFYHVARLS 803

  Fly   784 KSRQIKNRVRAIHTMATDDGRRVNFHPSS 812
            ||...|         .....:.|..||:|
Mosquito   804 KSGNYK---------TVKHNQDVMIHPNS 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	172/504 (34%)
		OB_NTP_bind	767..856	CDD:400182	13/46 (28%)
l(2)37Cb	XP_319843.5	None