Protein Alignment Ns4 and gnl2

DIOPT Version :9

• Sequence 1: NP_610055.1
• Gene: Ns4 / 35338
• FlyBaseID: FBgn0032882
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_998389.1
• Gene: gnl2 / 793727
• ZFINID: ZDB-GENE-040426-2317
• Length: 727
• Species: Danio rerio
• Alignment Length: 652
• Identity: 142/652 - (21%)
• Similarity: 234/652 - (35%)
• Gaps: 201/652 - (30%)

  Fly    14 KKKDQMLQKRNTKGPPKYLRSTQESYEDSDVPETTRKLMEQPFARGGNRNKNVNRYNLQFYQEGK 78
            |:.:...||:......|.::..|  |:::..|.|..::  :|..:.....|.:.:.:||.:||
Zfish    39 KRLNMYRQKQRCNSRGKVIKPLQ--YQNTVAPGTVARV--EPNIKWFANTKVIKQSSLQKFQE-- 97

  Fly    79 KELEQMKQEGFK--------PF-----------EKLSPAQREVDDRYFAGCDFPVRPPWTLTESK 124
             |:..:|::.::        |.           .|:.....|..:..|.......||..::.|.|
Zfish    98 -EMNAVKKDPYRVVMRQSKLPMSLLHDRIKAHNSKVHILDTETFETTFGPKAQRKRPNLSVGELK 161

  Fly   125 E--------------ELDR---TENRYFKEYV-DELQKKQRAGDSKELSLFELNLETWRQLWRVL 171
            |              |.||   :|:...||.. :|:.||   |.||.:         |.:|::|:
Zfish   162 EFAEQAEVSAQSYSAEKDRDLVSEDSGVKEEAREEIFKK---GQSKRI---------WGELYKVI 214

  Fly   172 EFSDILLIIVDVRYATLMFPPSLYDYIINTLK-----KHAIVVFNKVDLVEPHAVVAWRQYFRDR 231
            :.||:::.::|.|........|:..|    ||     ||.|.|.||.||:.......|.......
Zfish   215 DSSDVIIQVLDARDPMGTRSQSIETY----LKKEKPWKHLIFVLNKCDLIPTWVTKHWVAVLSQE 275

  Fly   232 YPQLPVVLFASFLPRSRKGSQRGPQAHRRSMEGVYNIYKECQRYVQGEVDLTTWEQKIREDMRSD 296
            ||.|  ...||......|||.                           :.|.....|:..|.:.
Zfish   276 YPTL--AFHASLTNSFGKGSL---------------------------IQLLRQFGKLHSDKKQ- 310

  Fly   297 QLDILDEISTAVEGELKISSSIDTTPHEHVKYHSGVLTIGCIGFPNVGKSSLINALKGRKVVSVS 361
                                                :::|.||:|||||||:||.|:.:||.:|:
Zfish   311 ------------------------------------ISVGFIGYPNVGKSSIINTLRSKKVCNVA 339

  Fly   362 RTPGHTKHFQTIFLTPLVRLCDCPGLVFPSSTPKSLQVLLGSFPISQLAVPYRSLKFLGEHLN-- 424
            ...|.||.:|.|.|...:.|.||||:|:||...::..||.|...:.::..|       .:|:.
Zfish   340 PLAGETKVWQYITLMRRIFLIDCPGVVYPSDDSETDIVLKGVVQVEKIRNP-------EDHIGAV 397

  Fly   425 LPQLLRLHLPEDY--DEW-SAVAISDAWAYKRGFLTAKAARPDRYRAANHILRMCLAGQQMLVLQ 486
            |.:....::.:.|  ..| ||....:..|::.|.| .|...||....:..:|.....|:    :.
Zfish   398 LERAKAEYIQKTYRIPSWSSAEDFLEKLAFRTGKL-LKGGEPDLPTVSKMVLNDWQRGR----IP 457

  Fly   487 FY--PPGFE--------------------ERREHWLQHPDVGEVKKYQQVE---LDEPESETNGD 526
            |:  |||.|                    :..|:.|:..||.|....|..|   |.:.:.|....
Zfish   458 FFVKPPGVETDEENKAQAMLEMPEMESEMDELENRLEAQDVEEASSSQHEEQKLLKKKKEEVQKL 522

  Fly   527 TSSV----------------------------CSDTADSEDEDEDSSNDETNADEEECGIREDAP 563
            .:.|                            .|.:.|.|:|:|:...|:....|||.|.:::..
Zfish   523 FNDVKQNFGKINVAPEFSEEDLVPVEMPDMMDASGSEDEENEEEEEEEDDEEKAEEETGEQQEEE 587

  Fly   564 RS 565
            .|
Zfish   588 SS 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns4	NP_610055.1	HSR1_MMR1	163..390	CDD:206750	59/231 (26%)
		GTPase_YlqF	165..474	CDD:274669	76/318 (24%)
gnl2	NP_998389.1	NGP1NT	44..174	CDD:285379	24/136 (18%)
		RbgA	198..475	CDD:224083	89/370 (24%)
		NGP_1	209..365	CDD:206751	56/225 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910