Protein Alignment Ns4 and gnl1

DIOPT Version :9

• Sequence 1: NP_610055.1
• Gene: Ns4 / 35338
• FlyBaseID: FBgn0032882
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_001072441.1
• Gene: gnl1 / 779895
• XenbaseID: XB-GENE-481292
• Length: 612
• Species: Xenopus tropicalis
• Alignment Length: 631
• Identity: 254/631 - (40%)
• Similarity: 355/631 - (56%)
• Gaps: 77/631 - (12%)

  Fly     1 MPQQRRKVAFSGKKKKDQMLQKRNTK-GPPKYLRSTQES--------YEDSDVPET------TRK 50
            ||   ||..||.|:||.|:..||..| ||.:..|:...|        .|::|..::      .|:
 Frog     1 MP---RKKPFSNKQKKKQLQDKRERKRGPSEQGRAESNSRSGSRERWEENTDTSDSESLRPQLRR 62

  Fly    51 LMEQP-FARGGNRNKNVNRYNLQFYQEGKKELEQMKQEGF-KPFEKLSPAQREV--DDRYFAG-- 109
            :.:|| ..:.|.||.:.|||.|.|.:|.|:|:||.|:... |..|.:..::.||  |..|..|
 Frog    63 VNQQPQIFKPGERNYDPNRYRLYFEKETKEEIEQRKKIALEKILEPVPESELEVHIDQIYRPGSV 127

  Fly   110 CDFPVRPPWTLTESKEELDRTENRYFKEYVDELQKKQRAGDSKELSLFELNLETWRQLWRVLEFS 174
            .|||.||.||...|||.:...|.:.||||   |||...:.:.:|||.|:.|||||||||||||.|
 Frog   128 LDFPKRPAWTYEMSKEAVQSREEKAFKEY---LQKIYESHNPRELSYFDHNLETWRQLWRVLEMS 189

  Fly   175 DILLIIVDVRYATLMFPPSLYDYIINTLKKHAIVVFNKVDLVEPHAVVAWRQYFRDRYPQLPVVL 239
            ||:|:|.|:|:..|.|.|:||||:...|.:..|:|.||.||..|..||||:.||:.::|::.||.
 Frog   190 DIILLITDIRHPVLHFSPALYDYVTQELGRSLILVLNKTDLAPPSLVVAWKHYFQAKFPKVHVVC 254

  Fly   240 FASFLPRSRKGSQRGPQA----HRR------SMEGVYNIYKECQRYVQGEVDLTTWEQKIREDM- 293
            |.|: ||..: .::.|.|    .||      |..|...:.:.|:.....:||||:|.:||..|.
 Frog   255 FTSY-PRHPE-EEQDPSAVFKKRRRKRRVWSSALGPSQLLRACEVITAEKVDLTSWREKIERDSA 317

  Fly   294 --------RSDQLDILDEISTAV-----EGELKISSSIDTTPHEHVKYHSGVLTIGCIGFPNVGK 345
                    ...|.:..||::..|     :.||...||        ..|..|||:|||:|||||||
 Frog   318 ALCNPASEEGTQDEETDELNAVVSHQITDAELGAPSS--------ELYKDGVLSIGCVGFPNVGK 374

  Fly   346 SSLINALKGRKVVSVSRTPGHTKHFQTIFLTPLVRLCDCPGLVFPSSTPKSLQVLLGSFPISQLA 410
            |||||.|.|:|:|||||||||||:|||.:|||.|||||||||:|||...:..|:|.|.:||:|:.
 Frog   375 SSLINGLVGKKIVSVSRTPGHTKYFQTYYLTPTVRLCDCPGLIFPSLIDRQQQILAGIYPIAQIQ 439

  Fly   411 VPYRSLKFLGEHLNLPQLLRLHLPEDYD-EWSAVAISDAWAYKRGFLTAKAARPDRYRAANHILR 474
            .||.|:.:|...:.:||||:|..|...: .|:|.:|.:|||.|||:.||||:|.|.|||||.:||
 Frog   440 EPYTSVGYLSCRIPVPQLLKLPQPSGVEGGWTAWSICEAWADKRGYKTAKASRSDTYRAANSLLR 504

  Fly   475 MCLAGQQMLVLQFYPPGFEERREHWLQHPDVGEVKKYQQVE---LDEPESETNGDTSSVCSDTAD 536
            :.:.|:..|.::  |||:..::|.|.|||:..|:..:.|.:   .::|.|....:...:.|...:
 Frog   505 LAVDGRLCLCMR--PPGYSVQKEAWQQHPETKEMAVHSQAQGQANNDPSSGREEEEEEISSSGEE 567

  Fly   537 SEDEDEDSSNDETNADEEECGIREDAPRSR-------NVFALLEDD 575
            .|::|.|:..:|   ||||...:....|..       |.|.||.:|
 Frog   568 EEEQDRDADEEE---DEEEDPTQSQHKRGNKNKVTDINPFELLGED 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns4	NP_610055.1	HSR1_MMR1	163..390	CDD:206750	116/250 (46%)
		GTPase_YlqF	165..474	CDD:274669	153/333 (46%)
gnl1	NP_001072441.1	RbgA	174..513	CDD:224083	161/348 (46%)
		HSR1_MMR1	178..419	CDD:206750	116/250 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	190	1.000	Domainoid score	I3198
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H3862
Inparanoid	1	1.050	400	1.000	Inparanoid score	I1882
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206558at33208
OrthoFinder	1	1.000	-	-		FOG0008221
OrthoInspector	1	1.000	-	-		oto103365
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5461
SonicParanoid	1	1.000	-	-		X6193
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.090