Protein Alignment Ns4 and Noa1

DIOPT Version :9

• Sequence 1: NP_610055.1
• Gene: Ns4 / 35338
• FlyBaseID: FBgn0032882
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_062810.1
• Gene: Noa1 / 56412
• MGIID: 1914306
• Length: 693
• Species: Mus musculus
• Alignment Length: 586
• Identity: 114/586 - (19%)
• Similarity: 160/586 - (27%)
• Gaps: 279/586 - (47%)

  Fly   110 CDFPVR-----------PPWTLTESKEELDRTENRY-FKEYV------------DELQKKQRAGD 150
            |:.|:|           |..|.||...|...||.|: |.|||            .||::.|:...
Mouse    36 CEVPIRQRASSLGRRVPPSSTATEDYAEGPDTEERFLFPEYVPERTPEEQVRELQELRELQQLQQ 100

  Fly   151 SKELSLFELNLETWRQLWR-------VLEFSDI-------------------------------- 176
            .||....:...|..:|..|       |.||.|.
Mouse   101 EKERERLQQREERLQQKLRAGFRTLPVPEFPDASVPPSGIYCSGCGAELHCQHPGLPGYLPEEKF 165

  Fly   177 -------------------LLI--------------IVDVRYATLMFP-PSLYDYIINTL----- 202
                               ||:              .:::..|.|..| |:|..|::|.|
Mouse   166 RDAAQAEGGPARTVCQRCWLLVHHGRALRLQVSRDQYLELVSAALRRPGPALVLYMVNLLDLPDA 230

  Fly   203 ----------KKHAIVVFNKVDLVEPHAVVAWRQYFRDRYPQLPVVLFASFLPRSRK-------- 249
                      .|..||:.|||||:...|                    ..:|.|.||
Mouse   231 LLPDLPKLVGPKQLIVLGNKVDLLPQDA--------------------PGYLKRLRKRLWDDCIR 275

  Fly   250 -------GSQRGPQAHRRSMEGVYNIYKECQRYVQGEVDLTTWEQKIREDMRSDQLDILDEISTA 307
                   |.| |||                  |..|:..|    ::|:....|.:      ..|.
Mouse   276 AGLVVAPGHQ-GPQ------------------YPAGDEPL----EEIKNQNPSSR------SRTV 311

  Fly   308 VEGELKISSSIDTTPHEHV-------KYHSGVLTIGCIGFPNVGKSSLINAL--------KGRKV 357
            |:....||:.......|.:       :|...|..:|.   .|.|||:|.|.|        ||.:.
Mouse   312 VKDVRLISAKTGYGVEEMISALQRSWRYRGDVYLVGT---TNAGKSTLFNTLLESDYCTAKGSEA 373

  Fly   358 V---SVSRTPGHTKHFQTIFLTPLVRLCDCPGLVFPSSTPKSLQVLLGSFPISQLAVPYRSLKFL 419
            :   ::|..||.|.:.                |.||...|                .|||..|
Mouse   374 IDRATISPWPGTTLNL----------------LKFPICNP----------------TPYRMFK-- 404

  Fly   420 GEHLNLPQLLRLH-----LPEDYDEWSAVAISDAWAYKRGFLTAKAARPDRYRAANHILRMCLAG 479
                   :..||.     ..||..|.....::.  ..|.|::..:..|...|...
Mouse   405 -------RQRRLQEDATKAEEDLSEEEQSQLNQ--LKKHGYIVGRVGRTFSYSRE---------- 450

  Fly   480 QQMLVLQF------YPPGFEERREHWLQHPDVGEVKKYQQVELDEPES--------ETNGDTSSV 530
            |..:..:|      :..|.|         |.|...|..:|:|| .||.        :|.|.|...
Mouse   451 QDEVPFEFDADSLAFDMGSE---------PVVSVCKSTKQIEL-TPEDVKDAHWFYDTPGITKES 505

  Fly   531 C 531
            |
Mouse   506 C 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns4	NP_610055.1	HSR1_MMR1	163..390	CDD:206750	61/347 (18%)
		GTPase_YlqF	165..474	CDD:274669	77/434 (18%)
Noa1	NP_062810.1	TMEM247	<33..>129	CDD:292084	24/92 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..67		5/23 (22%)
		Med21	<79..120	CDD:288119	7/40 (18%)
		PRK13796	140..655	CDD:237511	87/482 (18%)
		YqeH	180..396	CDD:206748	57/283 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	286..307		8/42 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900