Protein Alignment Ns4 and nst-1

DIOPT Version :9

• Sequence 1: NP_610055.1
• Gene: Ns4 / 35338
• FlyBaseID: FBgn0032882
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_495749.1
• Gene: nst-1 / 174329
• WormBaseID: WBGene00003821
• Length: 556
• Species: Caenorhabditis elegans
• Alignment Length: 596
• Identity: 127/596 - (21%)
• Similarity: 216/596 - (36%)
• Gaps: 152/596 - (25%)

  Fly    13 KKKKDQMLQKRNTKGPPKYLRSTQESYEDSDVPETTRKLMEQPFARGGNRNKNVNRYNLQFYQEG 77
            ||.:|   ..|..|...|...:|.:..:...||.:.      ||...........|..::..||.
 Worm    23 KKVRD---HNRKVKKEAKKNGTTNKKEKTISVPNSC------PFKEEILVQAEQEREKIKVRQEA 78

  Fly    78 KKE------LEQMKQEGFKPFE----KLSPAQREVDDRYFAGCDFPVRPPWTLTESKEELDRTEN 132
            .||      :|:.|......||    |.|....|.|.:..:..:            .|:.:..::
 Worm    79 AKEAAKIHRIEKRKNNLPANFESMVAKASKQGTEFDKKVASAAE------------HEKFNTLDD 131

  Fly   133 RYFKEYVDELQKKQRAGDSKELSLFELNLETWRQLWRVLEFSDILLIIVDVRYATLMFPPSLYDY 197
            :..|.|..|::|                         .:|.:|:::.::|.|........|:.|.
 Worm   132 KTIKAYASEVRK-------------------------TVEIADVIIQVLDARDPLGSRSKSVEDQ 171

  Fly   198 IINTLKKHAIVVFNKVDLVEPHAVVAWRQYFRDRYPQLPVVLFASFLPRSRKGSQRGPQAHRRSM 262
            ::.. .|..:::.||:|||....|..|.:|.|.   |.|.:.|.:
 Worm   172 VLKG-GKRLVLLLNKIDLVPRENVQKWLEYLRG---QFPTIAFKA-------------------- 212

  Fly   263 EGVYNIYKECQRYVQGEVDLTTWEQKIREDMRSDQLDILDEISTAVEGELKISSSIDTTPHEHVK 327
                                :|.|||......:..:....|.|..|..::.:....:...::.:|
 Worm   213 --------------------STQEQKSNIGRFNSAILNNTETSKCVGADIVMKILANYCRNKDIK 257

  Fly   328 YHSGVLTIGCIGFPNVGKSSLINALKGRKVVSVSRTPGHTKHFQTIFLTPLVRLCDCPGLVFPSS 392
            ..   :.:|.:|||||||||:||:||.||..:|...||.||..|.:.|...:||.|.||::..|.
 Worm   258 TS---IRVGVVGFPNVGKSSVINSLKRRKACNVGNLPGITKEIQEVELDKNIRLIDSPGVILVSQ 319

  Fly   393 TPKSLQ----VLLGSFPISQLAVPYR---------SLKFLGEHLNLPQLLRLHLPEDYDEWSAVA 444
              |.|.    .|..:..:..|..|..         |.:.:..|.||...      ...|::.|..
 Worm   320 --KDLDPIEVALKNAIRVDNLLDPIAPVHAILRRCSKETIMLHYNLADF------NSVDQFLAQL 376

  Fly   445 ISDAWAYKRGFLTAKAARPDRYRAANHILRMCLAGQQMLVLQFY--PPGFEERREHWLQHPDVGE 507
            .......:||      ||||...||..:|.....|:    |::|  ||.....:|..:...:|
 Worm   377 ARRIGKLRRG------ARPDVNAAAKRVLNDWNTGK----LRYYTHPPEQGTAKEDIVVPAEV-- 429

  Fly   508 VKKY-QQVELDEPESETNG-------DTSSVCSDTADSEDEDEDSSNDETNADEEECGIREDAPR 564
            |.:: ::.::|....|.|.       ::..:....:|.|::|:|..  ||:.:|:    ::....
 Worm   430 VSQFSKEFDIDAIAEEQNQIVEGLPMESDIIAPHNSDEEEDDDDEM--ETDVNEK----KQTVTS 488

  Fly   565 SRNVFALLEDD 575
            .|.|....:||
 Worm   489 GRKVKGPTKDD 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns4	NP_610055.1	HSR1_MMR1	163..390	CDD:206750	55/226 (24%)
		GTPase_YlqF	165..474	CDD:274669	75/321 (23%)
nst-1	NP_495749.1	GN3L_Grn1	17..84	CDD:285863	16/69 (23%)
		RbgA	140..439	CDD:224083	86/390 (22%)
		Nucleostemin_like	149..314	CDD:206753	53/211 (25%)
		P-loop_NTPase	263..401	CDD:304359	49/151 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810